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cancer

# Episode Title Description People Date
1 Creative Commons Effect of metformin on breast cancer metabolism Dr Simon Lord presents a clinical study to understand the effect of metformin - one of the most commonly prescribed treatments worldwide for diabetes - on breast cancer metabolism. Simon Lord 16 Jan 2019
2 Creative Commons Prostate cancer genomic surgery: A shifting paradigm In the first half, Dr Alastair Lamb discusses the problem with prostate cancer and what it is that needs to be addressed, his previous research and future plans for research. Alastair Lamb 30 Apr 2018
3 Creative Commons Oesophageal Cancer: Past, Present and the Future Professor Tim Underwood takes us through the history of oesophageal cancer, where we are now, and some of the science that is done to ask questions about where we might go with the treatment of oesophageal cancer. Tim Underwood 16 Apr 2018
4 Creative Commons Upper GI Surgery Dr John Findlay (Oxford University) presents 'Heavy Petting in Oesophago-gastric Cancer’ and Mr Nick Maynard (Oxford University) presents ‘How Much Should we Tell the Public About Outcomes from Oesophagectomy?’ Nick Maynard, John Findlay 28 Feb 2018
5 The 100,000 Genomes Project Ms Jennifer Whitfield talks about the 100,000 Genomes Project, which aims to establish a new genomic medicine service through the NHS by sequencing the entire genomes of around 70,000 people with rare inherited diseases or cancer. Jennifer Whitfield 10 Apr 2017
6 Lights, Camera, Immuno-action! Research on cancer immunotherapy and its implications for the clinic Melissa Bedard explains the body’s lack of an immune response to cancer cells through an analogy with spy movies. Melissa Bedard 03 Apr 2017
7 Creative Commons Epigenetic modifications and cancer Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer. Skirmantas Kriaucionis 14 Dec 2016
8 Creative Commons Epigenetic modifications and cancer Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer. Skirmantas Kriaucionis 14 Dec 2016
9 Can bubbles help cure cancer? On this episode, can bubbles cure cancer? Eleanor Stride 02 Dec 2016
10 Creative Commons Gastrointestinal cancers Dr Claire Palles studies whole genome sequencing data and targeted analyses with the aim of discovering genetic variants that affect susceptibility to colorectal cancer and Barrett’s oesophagus. Claire Palles 30 Nov 2016
11 Creative Commons Gastrointestinal cancers Dr Claire Palles studies whole genome sequencing data and targeted analyses with the aim of discovering genetic variants that affect susceptibility to colorectal cancer and Barrett’s oesophagus. Claire Palles 30 Nov 2016
12 Ovarian metastases from gastrointestinal tract malignancy Mr Brendan Moran discusses cancer metastases to the ovary. Mr Moran is a general and colorectal surgeon at Hampshire Hospitals NHS Foundation Trust. Brendan Moran 18 Nov 2016
13 Is my bacon sandwich really going to kill me? Statistician Dr Jennifer Rogers discusses the numbers linked to processed meat and bowel cancer. Jennifer Rogers 25 Oct 2016
14 The Jenkin Lecture - Engineering Tomorrow's Therapies Professor Constantin Coussios (Magdalen), Professor of Biomedical Engineering, gives the 2016 annual Jenkin Lecture, on 17th September 2016. Constantin Coussios 21 Sep 2016
15 'Light' Part 3 - How does sunlight damage DNA? Once we've received our genetic make-up from our parents our genomes are stable, right? What causes mutations in our DNA as we live and grow, and how do our cells repair damage? Catherine Green 03 Aug 2016
16 Creative Commons Repairing DNA damage Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer in humans. Ross Chapman 28 Apr 2016
17 Targeting drug discovery The development of new medicines is dependent on the identification of novel drug targets. Kilian Huber 28 Apr 2016
18 Repairing DNA damage Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer in humans. Ross Chapman 28 Apr 2016
19 Targeting drug discovery The development of new medicines is dependent on the identification of novel drug targets. Kilian Huber 28 Apr 2016
20 Creative Commons Cleaning up misfolded proteins Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases. John Christianson 04 Feb 2016
21 Cleaning up misfolded proteins Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases. John Christianson 04 Feb 2016
22 Creative Commons Targeting cancer mechanisms Professor Robert Gilbert's research focuses on the molecular mechanisms underlying membrane pore formation and cell adhesion. Robert Gilbert 07 Jan 2016
23 Targeting cancer mechanisms Professor Robert Gilbert's research focuses on the molecular mechanisms underlying membrane pore formation and cell adhesion. Robert Gilbert 07 Jan 2016
24 Genomic revolution and its impact on prostate cancer care Professor Ash Tewari talks about the genomics of prostate cancer and the implications for managing high risk disease. Ash Tewari 05 Jan 2016
25 Creative Commons Radiotherapy: What is it? How does it work? And how will it change? Radiotherapy has been going on since 1896, only months after the discovery of X-rays.  We will explore what it is, how it works, and examine the change from X-ray beams to particle guns. Martin Christlieb 11 Dec 2015
26 Creative Commons Melanoma Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to metastasise, it becomes very difficult to treat. Colin Goding 05 Oct 2015
27 Creative Commons Targeting epigenetics to treat cancer Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors. Panagis Filippakopoulos 05 Oct 2015
28 Creative Commons Melanoma Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to metastasise, it becomes very difficult to treat. Colin Goding 05 Oct 2015
29 Creative Commons Targeting epigenetics to treat cancer Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors. Panagis Filippakopoulos 05 Oct 2015
30 Interview with Michael Docherty We catch up with Cancer Research UK's Director of Digital on fundraising in the digital age. Michael Docherty 03 Aug 2015
31 Fundraising through Digital Michael Docherty (Cancer Research UK) on how clicktivists, slacktivists and hacktivists are helping us beat cancer sooner. Michael Docherty 03 Aug 2015
32 Creative Commons Human Cancer Genetics Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression and treatment of human cancer. Gareth Bond 11 Mar 2015
33 Human Cancer Genetics Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression and treatment of human cancer. Gareth Bond 11 Mar 2015
34 Creative Commons Cancer predisposition and evolution Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stage. A better understanding of how and why cancers grow also helps develop improved treatments. Ian Tomlinson 09 Feb 2015
35 Creative Commons Cancer Informatics Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of this variability at molecular level will help us better tailor treatments to individual cancer patients. Benjamin Schuster-Böckler 09 Feb 2015
36 Cancer predisposition and evolution Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stage. A better understanding of how and why cancers grow also helps develop improved treatments. Ian Tomlinson 09 Feb 2015
37 Cancer Informatics Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of this variability at molecular level will help us better tailor treatments to individual cancer patients. Benjamin Schuster-Böckler 09 Feb 2015
38 Can we starve tumours? Oxford Chemistry joins Cancer Research UK in the fight for the cure A film produced as part of the Oxford Open Doors 2014, reflecting on some of the exciting cancer research being undertaken in the Oxford Chemistry Department. With Professor Chris Schofield, Oxford University, and Charlotte Richards, Cancer Research UK. Chris Schofield, Charlotte Richards 16 Jan 2015
39 Creative Commons Prof Xin Lu: Women in Science Every cloud has a silver lining: optimisism and persistence Xin Lu 10 Dec 2014
40 DNA replication and Cancer DNA replication and Cancer Catherine Green 10 Dec 2014
41 Cancer and innate immunity Inflammatory signalling Mads Gryd-Hansen 10 Dec 2014
42 Stem cells and cancer Adult gastrointestinal stem cells Simon Leedham 10 Dec 2014
43 Creative Commons DNA replication and Cancer DNA replication and Cancer Catherine Green 10 Dec 2014
44 Creative Commons Prof Xin Lu: Women in Science Every cloud has a silver lining: optimisism and persistence Xin Lu 10 Dec 2014
45 "Matters of Scale" - Complete Episode The issues of scale are investigated – from how properties change at very small scales, to the vastness of the Universe. Includes parts 1, 2 and 3. Pedro Ferreira, Alan Barr, Sylvia MacLain, Sonia Trigueros 09 Oct 2014
46 "Matters of Scale" Part 3 - Nanomedicine Dr Sonia Trigueros explains how she is using nanotechnologies to create targeted drug delivery systems. Chemotherapy is a particularly harmful treatment, with patients losing their hair and suffering from infections due to damage to their immune systems. Sonia Trigueros, Chris Lintott 08 Oct 2014
47 Creative Commons Stem cells and cancer Adult gastrointestinal stem cells Simon Leedham 07 Oct 2014
48 Creative Commons Cancer and innate immunity Inflammatory signalling Mads Gryd-Hansen 07 Oct 2014
49 Mass spectrometry: how does it work, and why should you care? From cutting-edge cancer research to sustainable fish farming, Dr James McCullagh explains the importance of mass spectrometry. James McCullagh 19 Jun 2014
50 Inside NMR Spectroscopy Dr Tim Claridge takes apart an NMR machine to show us how this technique is used in research with application in human health and beyond. Tim Claridge 19 Jun 2014
51 Why there are no three-headed monsters, resolving some problems with brain tumours, divorce prediction and how to save marriages Professor James D Murray, Professor Emeritus of Mathematical Biology, University of Oxford & Senior Scholar, Applied and Computational Mathematics, Princeton University, gives the annual Hooke Lecture. James D Murray 21 Mar 2014
52 Creative Commons Psychological medicine Interview with Professor Sharpe about psychological medicine and his randomised controlled trial investigating the treatment of depression in people with cancer. Michael Sharpe 15 Oct 2013
53 Conclusion: How Chemistry Research Impacts Human Health Wrapping up this series on human health, Dr Emily Flashman talks about her work studying the mechanisms by which our bodies respond to low levels of oxygen. Emily Flashman 19 Jul 2013
54 Synthesizing Anti-Cancer Drugs from Nature Chemicals found in nature can have incredibly useful functionality, including anti-malarial and anti-cancer properties. However, they are usually found in small amounts. Chris Jones 19 Jul 2013
55 Epigenetics and New Anti-Cancer Treatments At the interface of chemistry, biology, and medicine, Cyrille Thinnes, a DPhil student in the Schofield Group, shares his research into the next generation of anti-cancer treatments. Cyrille Thinnes 19 Jul 2013
56 Introduction: How Chemistry Research Impacts Human Health To truly understand disease, we need to understand the underlying chemical processes that direct human biology. Dr Emily Flashman introduces some of the research in the Department of Chemistry that will help improve our health in future. Emily Flashman 19 Jul 2013
57 Creative Commons Development of chemical probes Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. Stefan Knapp 21 May 2013
58 Creative Commons Development of chemical probes Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. Stefan Knapp 21 May 2013
59 Creative Commons The lymphatic system in immunity and cancer Professor David Jackson tells us about the role of the lymphatic system in immunity and cancer. David Jackson 29 Apr 2013
60 Creative Commons The lymphatic system in immunity and cancer Professor David Jackson tells us about the role of the lymphatic system in immunity and cancer. David Jackson 29 Apr 2013
61 Creative Commons Cancer Immunlogy Professor Vincenzo Cerundolo tells us how research in immunology leads to the development of new cancer treatments. Vincenzo Cerundolo 25 Mar 2013
62 Creative Commons Cancer Immunlogy Professor Vincenzo Cerundolo tells us how research in immunology leads to the development of new cancer treatments. Vincenzo Cerundolo 25 Mar 2013
63 Creative Commons Cancer and regenerative medicine Professor Xin Lu talks about the links between cancer and regenerative medicine. Xin Lu 22 Mar 2013
64 Creative Commons Cancer and regenerative medicine Professor Xin Lu talks about the links between cancer and regenerative medicine. Xin Lu 22 Mar 2013
65 Creative Commons Biology, Chemistry and Biochemistry at Oxford: a guide for prospective undergraduate students This light-hearted talk gives you the chance to hear three admissions tutors discuss what you can expect from their courses, and what the tutors are looking for when they select students. Martin Speight, Mark Wormald, Nick Green 04 Mar 2013
66 Creative Commons Radiation and Reason Professor Wade Allison gives a talk about his book 'Radiation and Reason; The Impact of Science on a Culture of Fear'. Wade Allison 14 Nov 2012
67 Creative Commons INDOX Cancer Research NetworK Dr Raghib Ali talks about INDOX, the cancer research network in India. Raghib Ali 09 Oct 2012
68 Creative Commons INDOX Cancer Research Network Dr Raghib Ali talks about INDOX, the cancer research network in India. Raghib Ali 09 Oct 2012
69 Creative Commons How can stem cells help in the treatment of cancer? One of the flipsides of ageing is cancer, characterised by cells that do not age. What can stem cell research learn from cancer cells to help prevent the degenerative illnesses associated with ageing? Colin Goding 20 Aug 2012
70 Creative Commons Cancer Metabolism Dr Patrick Pollard tells us about his research on cancer metabolism. Patrick Pollard 10 Jul 2012
71 Creative Commons Genome Integrity Dr Opher Gileadi tells us how cells maintain genome integrity and how we can use it in our fight against cancer. Opher Gileadi 01 Jun 2012
72 Creative Commons Genome Integrity Dr Opher Gileadi tells us how cells maintain genome integrity and how we can use it in our fight against cancer. Opher Gileadi 01 Jun 2012
73 Creative Commons Meat and Health In this Health, Environment and Development seminar, Peter Scarborough (a UL in Public Health) discusses the impact of achieving environmental sustainable diets on deaths from cardiovascular disease and cancer in the UK. 18 October 2011. Peter Scarborough 24 May 2012
74 Creative Commons Renal Disease Professor Chris Pugh tells us about the links between genetics, renal disease and oxygen sensing. Chris Pugh 11 Oct 2011
75 Creative Commons Palliative Care Dr Bee Wee tells us about Palliative Care in Oxford and her research on end of life care and fatigue. Bee Wee 30 Aug 2011
76 Creative Commons Role of Lifestyle and Diet in Cancer Professor Tim Key tells us about the role of life style and diet in the development of cancer. Tim Key 10 May 2011
77 Creative Commons Role of Lifestyle and Diet in Cancer Professor Tim Key tells us about the role of life style and diet in the development of cancer. Tim Key 10 May 2011
78 Creative Commons Chromatin Remodelling Dr Erika Mancini explains the role of chromatin in the regulation of gene transcription. Erika Mancini 15 Nov 2010
79 Cancer Research in India Part 2 Dr Vinod Raina, co-founder of the INDOX Cancer Research Network, discusses the key achievements of INDOX and the challenges involved in doing clinical trials in India. Vinod Raina, Vanita Sharma 17 Dec 2009
80 Creative Commons Breast Cancer: Causes and Prevention Dr Valerie Beral talks about her research into the causes of breast cancer, looking into the history of the cancer as well as offering ways of reducing the risk of contracting breast cancer. Valerie Beral 28 Oct 2009
81 Pathology in Africa Dr Kenneth Fleming discusses the work that Oxford University is doing to help improve pathology services in Africa. Kenneth Fleming 13 Aug 2009
82 Understanding cancer: News from the frontline This Oxford at Said seminar was dedicated to cancer research. Three researchers from the University of Oxford give insights into recent advances in the field of cancer cell biology, therapy and epidemiology. Jordon Raff, Gillies McKenna, Sir Richard Peto 04 Aug 2009
83 Childhood Cancer in the Developing World Professor Tim Eden talks about the challenges faced in curing childhood cancer in the developing world. Tim Eden, Vanita Sharma 16 Jun 2009
84 Richard Doll: his revolutionary life Conrad Keating, biographer of Richard Doll, lectures on the life of the cancer epidemiologist and lifelong socialist who contributed much to our understanding of the effects of smoking and changed the way we regard smoking and public health. Conrad Keating 28 Apr 2009
85 Alan Milburn on Cancer in Africa In this podcast, Alan Milburn, MP for Darlington and former Secretary of State for Health, explains the importance of international support to help improve cancer care in Africa, and talks about the challenges that must to be overcome. Alan Milburn, Vanita Sharma 27 Apr 2009
86 Chris Patten on Politics and Public Health Lord Patten, Chancellor of the University of Oxford, discusses his political perceptions of epidemiology in the UK, and in developing and emerging countries. Chris Patten 23 Apr 2009
87 Cancer Research in India Dr. Raghib Ali discusses cancer in India, why Oxford University became interested in this problem and how IndOx has helped to improve the standard of clinical trials in India. Raghib Ali, Vanita Sharma 05 Feb 2009
88 Cancer in Africa Professor David Kerr discusses the cancer burden in Africa, why he became interested in this problem, and how AfrOx is helping to improve the level of cancer care in Africa. David Kerr, Vanita Sharma 05 Feb 2009
89 David Kerr on Cancer Research Professor David Kerr discusses his work on colorectal cancer, the process of how new treatments are developed, the changes in the NHS that he has witnessed over his career, and how cancer care differs in developing countries. David Kerr, Vanita Sharma 05 Feb 2009
90 Thomas Helleday on Cancer Professor Helleday explains what cancer is, the problems of treating it, and the success of his own research in developing new treatments. Thomas Helleday 11 Sep 2008
91 Thomas Helleday on Cancer Professor Helleday explains what cancer is, the problems of treating it, and the success of his own research in developing new treatments. Thomas Helleday, Oliver Lewis 11 Sep 2008