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Professor Daniel Prieto-Alhambra

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Daniel Prieto-Alhambra, Professor of Pharmaco- and Device Epidemiology, 14 March 2023.
Topics discussed include (00:00:37) early interest in science and medicine, PhD studies in Barcelona, visiting PhD student at Oxford, health data sciences (00:02:42) use of existing data (routinely collected data and electronic medical records) for research into musculoskeletal conditions, comparison to clinical trials for research, including advantages of this kind of data; (00:06:18) curation of data and databases; (00:09:57) number of patients represented in study, types of questions investigated; (00:14:52) first awareness of COVID-19; (00:18:12) pivot towards working on COVID, including virtual study involving colleagues across the globe with the Observational Health Data Sciences and Informatics community, writing protocols on various studies including a study relating to repurposing of drugs; (00:23:13) hydroxychloroquine study and overlap with RECOVERY trial; (00:26:38) prediction and classification; (00:28:05) information flow between researchers and government; (00:29:48) work relating to candidate vaccines; (00:39:05) blood clotting; (00:41:24) Guillain-Barré syndrome, encephalomyelitis, and Bell’s palsy analysis; (00:46:00) long COVID; (00:52:06) current work relating to COVID; (00:53:05) predicting cancer, utilising artificial intelligence to classify cancer; (00:55:23) collaboration and competition during the pandemic; (00:56:16) personal threat from COVID-19; (00:58:00) remote working; (00:59:33) consideration of a return to clinical practice; (01:01:34) changes to working hours during the pandemic; (01:02:42) wellbeing during the pandemic; (01:03:44) changes in approach to work as a result of the pandemic.

Episode Information

Series
Collecting COVID: Oral Histories
People
Daniel Prieto-Alhambra
Georgina Ferry
Keywords
medical sciences
pharmacoepidemiology
medical records--data processing
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:05:25

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Dr Rajarshi Banerjee

Series
Collecting COVID: Oral Histories
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Georgina Ferry interviews Rajarshi Banerjee, CEO Perspectum and former student of Oxford Medical School, 14 March 2023.
Topics discussed include (00:00:08) early interest in science, entry into medical school at Oxford, interest in research, registrar training programme in cardiology and internal medicine, British Heart Foundation funding for a PhD; (00:04:21) PhD studies at Oxford on cardiac MRI (to discover whether people with excess bodyweight accumulated fat in their heart muscle and whether that fat impaired its function); (00:06:12) biomedical engineering; (00:07:34) quality of MRI imaging in 2008; (00:09:44) interest in improving MRI imaging; (00:14:01) liver disease research; (00:17:00) formation of company and founding of Perspectum in 2012, work with Sir Michael Brady, Matt Robson and Stefan Neubauer; (00:20:05) company progress; (00:25:22) first awareness of COVID-19; (00:29:59) multi-organ involvement and role of Perspectum; (00:33:23) CoverScan, including collaborators, long COVID; (00:43:39) adoption of the technology clinically, scan findings; (00:50:44) MRI units using CoverScan; (00:51:25) pivot towards this work during the pandemic and impact on the company; (00:54:28) community diagnostic centre; (01:01:52) current patient throughput, including patients with long COVID; (01:05:54) organs CoverScan investigates; (01:07:54) signs CoverScan investigates in organs; (01:10:19) expense of CoverScan and comparison to separate scans; (01:12:22) NICE; (01:14:35) patient groups; (01:18:13) personal threat from COVID-19; (01:20:38) sense of wellbeing whilst working during the pandemic; (01:22:19) changes in attitude to work as a result of the pandemic.

Episode Information

Series
Collecting COVID: Oral Histories
People
Rajarshi Banerjee
Georgina Ferry
Keywords
medical sciences
magnetic resonance imaging
clinical medicine
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:23:26

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Tony Brett

Series
Collecting COVID: Oral Histories
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Georgina Ferry interviews Tony Brett, Director of Medical Sciences Division IT Services, 28 February 2023.
Topics discussed include (00:00:23) early interest in science, degree in chemistry at Oxford, interest in IT and computers and work at Oxford at the Weatherall Institute of Molecular Medicine, roles at Corpus Christi and OUCS; (00:05:09) challenges in supporting academics; (00:07:11) scope of IT services across the university, demands on services as research becomes more data focused; (00:08:55) data centres; (00:12:18) first awareness of COVID-19; (00:14:05) impact on the Medical Sciences Division, including providing hardware and support to people working remotely, relationship with National Cyber Security Centre; (00:17:30) Early Alert Service; (00:23:10) big data studies; (00:23:45) investigating new technologies; (00:25:43) recruitment during the pandemic; (00:27:27) collaboration across departments; (00:28:45) interactions with IT teams in other universities; (00:30:31) success of the Early Alert Service; (00:33:15) current work; (00:36:05) personal threat from COVID-19; (00:37:35) changes to working hours, wellbeing; (00:40:22) social distancing regulations and impact on the MSD IT team; (00:43:01) lessons from the pandemic, including a paperless office; (00:46:01) Oxford transport, including cycling safety; (00:50:00) reflections on the pandemic; (00:51:17) changes to work perspective as a result of the pandemic.

Episode Information

Series
Collecting COVID: Oral Histories
People
Tony Brett
Georgina Ferry
Keywords
medical sciences
information technology
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 00:53:58

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Professor Sheetal Silal

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Sheetal Silal, Associate Professor (Department of Statistical Sciences, University of Cape Town) and Honorary Visiting Research Fellow in Tropical Disease Modelling (Nuffield Department of Medicine), 28 February 2023.
Topics discussed include (00:01:18) early interest in mathematics, database evidence making in health; (00:03:24) global health problem of malaria; (00:04:47) contribution of data science in combating and eliminating malaria; (00:07:13) global collaborations, including with colleagues at the University of Oxford and South America; (00:08:47) first awareness of COVID-19, involvement in the response; (00:11:45) model building during the pandemic; (00:16:18) government policy decisions based on modelling; (00:18:40) evolution of the pandemic in South Africa; (00:22:50) mortality rate and hospital capacity in South Africa; (00:25:35) projections and analyses of new variants; (00:30:31) compliance to public health regulations in South Africa; (00:37:10) CoMo Consortium; (00:38:12) shift of focus since COVID-19 on a variety of diseases, including hepatitis A; (00:40:34) teaching at Oxford, module lead on course Malaria Modelling for Strategy Design; (00:42:40) personal threat from COVID-19; (00:44:10) wellbeing of friends, family and colleagues; (00:49:01) working hours during the pandemic; (00:54:33) therapy and personal coping mechanisms; (00:56:00) personal reflections from the pandemic.

Episode Information

Series
Collecting COVID: Oral Histories
People
Sheetal Silal
Georgina Ferry
Keywords
medical sciences
statistics
malaria
communicable diseases
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:03:40

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Dr Ane Ogbe

Series
Collecting COVID: Oral Histories
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Georgina Ferry interviews Ane Ogbe, former Senior Immunologist (Frater Lab) and Group Leader (Evox Therapeutics), 23 Febrauary 2023.
Topics discussed include (00:00:48) early interest in science, studies in biomedical sciences, master's in molecular medicine with cancer research at Brunel University; (00:07:13) main arms of the immune system, difference between T cells and B cells; (00:12:57) move to Oxford working at the Nuffield Department of Medicine Research Building, pivot toward working on HIV; (00:19:04) move to Professor John Frater's laboratory, continued work on HIV; (00:24:47) first awareness of COVID-19; (00:28:45) understanding the immunology of COVID-19, including characterisation of immune response in healthcare worker cohort; (00:36:32) characterisation of vaccine immune responses, comparison of mRNA and adenoviral vectored vaccines; (00:37:49) sub-study relating to HIV vaccines, management of COVID-19 in HIV-infected people; (00:40:50) involvement in sample collection; (00:42:29) first paper on T cells in early 2020, research on cross-reactive responses; (00:48:20) collaboration during the pandemic; (00:50:55) leaving Oxford; (00:54:36) mentorship programme with the British Society for Immunology (BSI); (00:56:23) new opportunities, including in the biotechnology industry; (01:04:34) personal threat from COVID-19; (01:08:12) changes to working hours during the pandemic; (01:10:22) wellbeing support; (01:15:00) changes in approach to work as a result of the pandemic. Note: the following sections of audio are redacted (00:04:35) to (00:06:22); (00:12:18) to (00:12:45); (00:13:15) to (00:13:20); (00:21:01) to (00:21:13); (00:21:37) to (00:22:06); (00:23:11) to (00:23:33).

Episode Information

Series
Collecting COVID: Oral Histories
People
Ane Ogbe
Georgina Ferry
Keywords
medical sciences
immunology
HIV infections
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:19:46

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Professor Nicole Zitzmann

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Nicole Zitzmann, Professor of Virology and Principal Investigator (Department of Biochemistry), 22 February 2023.
Topics discussed include (00:00:31) studies in Germany, including study of Biology in Bonn, studies in English, biochemistry student in Dundee, Masters and PhD under supervisor Professor Mike Ferguson, move to Oxford in 1997 working at the Glycobiology Institute, mentorship of Barry Blumberg, iminosugars; (00:08:55) drugs targeting whole-cell process; (00:11:10) viruses worked on; (00:21:05) host-targeting drug side effects; (00:23:40) role of vaccines and drugs in tackling viruses; (00:27:22) first awareness of COVID-19, pivoting of work towards COVID-19, Sir William Dunn School containment level 3 laboratory; (00:33:32) screening of repurposed drugs; (00:45:00) SARS Tracker screening, Moonshot compounds; (00:46:35) research on iminosugars; (00:49:05) clinical trial obstacles; (00:50:50) funders and regulatory bodies; (00:54:10) Gaucher disease; (00:57:05) personal threat from COVID-19; (00:59:56) changes to work life during the pandemic, including remote working, Vaccine Identity Evaluation (VIE) project; (01:06:10) changes to working hours, group collaboration, achievement and mental wellbeing; (01:09:15) collaborations during the pandemic; (01:11:41) advantages of remote working; (01:14:34) changes in approach to work as a result of the pandemic. Note: the following sections of audio are redacted (00:19:15) to (00:19:21); (00:50:20) to (00:50:26); (00:56:17) to (00:56:32).

Episode Information

Series
Collecting COVID: Oral Histories
People
Nicole Zitzmann
Georgina Ferry
Keywords
physical sciences
biochemistry
antiviral agents
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:15:44

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Dr Chia Chen (Jane) Hsu

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Chia Chen (Jane) Hsu, Chief Operating Officer (SimCell) and former postdoctoral researcher (Institute of Biomedical Engineering), 20 February 2023.
Topics discussed include (00:00:40) early interest in science and engineering, studies in biomedical engineering, synthetic biology, PhD studies at Imperial College London, postdoctoral project at Oxford; (00:06:25) neuro engineering project at Oxford; (00:09:55) work in Professor Zhanfeng Cui's group and collaboration with Chinese Institutes including the Jiangsu Industrial Technology Partnership Research Institute, IMPACT project; (00:16:06) first awareness of COVID-19, including conference in Jiangsu; (00:17:37) pivoting of work of group towards COVID-19, emerging research group; (00:22:44) LAMP (loop-mediated isothermal amplification); (00:27:36) proof of principle, including use of synthetic DNA fragments and synthetic RNA; (00:30:35) performance of the nucleic acid test; (00:31:20) commercial partners, including formation of Oxsed; (00:34:29) use of tests, including at airports, training of airport staff; (00:38:46) pivoting of role away from postdoc position to join Oxsed; (00:40:39) product development tasks and challenges, including product development for other respiratory diseases; (00:43:45) current position at SimCell; (00:47:43) personal threat from COVID-19, use of PPE; (00:51:49) personal wellbeing and support; (00:54:14) positive changes to working as a result of the pandemic; (00:55:42) professional collaborations during the pandemic; (00:57:57) changes in approach to work, hopes for changes in the future.

Episode Information

Series
Collecting COVID: Oral Histories
People
Chia Chen (Jane) Hsu
Georgina Ferry
Keywords
engineering sciences
biomedical engineering
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration:

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Chris Price

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Chris Price, Divisional Registrar and Chief Operating Officer for Medical Sciences, 8 February 2023.
Topics discussed include (00:00:34) work at the University of Oxford since 1993, sociology degree, work with Sir Richard Peto and Sir Rory Collins in the Clinical Trial Service Unit ; (00:01:52) interest in medical sciences, work in professional services roles; (00:03:40) scale of Medical Sciences Division; (00:05:06) scope of role as Registrar; (00:06:31) working with clinicians and medical colleagues; (00:08:06) challenging and rewarding projects worked on up to 2019; (00:12:52) first awareness of COVID-19; (00:17:07) coordination of the scientific community at Oxford, led by Richard Cornall and daily meetings, creation of group led by senior scientists; (00:21:55) movement of the Medical Sciences Divisional Office and closure; (00:26:31) COVID-19 response fundraising; (00:30:34) main challenges in supporting scientists; (00:37:46) University response; (00:42:45) supply issues within the NHS, including access to PPE and swabs; (00:48:18) setting up in-house PCR testing service for university staff and students; (00:53:50) involvement in lateral flow device testing across the university; (00:58:45) percentage of researchers in the division working on COVID-19, other staff in the division and remote working; (01:03:02) staff wellbeing and support; (01:07:08) personal threat from COVID-19; (01:12:27) university-wide collaborations, ability to work together as a result of the pandemic and changes as a result of this; (01:21:58) lasting legacies, including Pandemic Sciences Institute; (01:26:21) changes in approach to work, as a result of the pandemic.

Episode Information

Series
Collecting COVID: Oral Histories
People
Chris Price
Georgina Ferry
Keywords
medical sciences
research
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 05/07/2023
Duration: 01:29:38

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Kate Fulcher

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Analysis of Pigments on Painted Byzantine and Japanese Manuscripts

Series
The Bodleian Libraries (BODcasts)
Embed
An introduction to the analysis of painted Byzantine and Japanese manuscripts by the Bodleian Libraries' new Heritage Scientist.
The post of Heritage Scientist at the Bodleian Libraries was re-instated at the beginning of 2023, enabling the analysis of manuscripts in the library’s collection. The focus so far has been on Byzantine manuscripts from the 10th to 13th centuries, and Japanese scrolls from the 17th century which contain painted pictures.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
The Bodleian Libraries (BODcasts)
People
Kate Fulcher
Keywords
pigments
manuscripts
heritage
paint
art
Department: Bodleian Libraries
Date Added: 04/07/2023
Duration: 00:36:24

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