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Julia Hippisley-Cox

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Kristin van Zwieten

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Dr Samantha Vanderslott

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Samantha Vanderslott, University Research Lecturer (Oxford Vaccine Group), 18 March 2022.
Topics discussed include (00:00:35) SV's early studies, undergraduate degree in Economics and International Development, interest in politics and governance with a Masters undertaken at Oxford, work for two years with the UK Government (Business, Innovation and Skills), interest in research and PhD at UCL (University College London) particularly Sociology of Science with research topic of 'Neglected Tropical Diseases,' and later work at Oxford with the Oxford Vaccine Group; (00:05:30) pre-pandemic work including the Collective Responsibility for Infectious Disease programme, including interdisciplinary research, individual and collective responsibility, work on typhoid; (00:11:20) research into attitudes to vaccination, including particular groups in the USA and Australia; (00:16:15) SV's first memory of COVID-19 in December 2019 and early 2020, conversations with Claas Kirchhelle and launch of exhibition 'Alice in Typhoidland'; (00:20:36) changes to research focus as a result of COVID-19, including work relating to views around vaccines, other health society issues including misinformation, qualitative work with trial participants; (00:23:35) data gathering methods, including interviews and focus groups; (00:25:20) research into trial participants, including survey questions asked relating to motivations, attitudes to risk, reaction of friends and family, wider views about vaccines; (00:28:40) trial participant interviews, including the varying experiences of participants; (00:30:40) questions asked of participants, including relating to vaccine equity, views on whether they had received the vaccine or placebo, behavioural changes after vaccination; (00:34:48) use of social media for data analysis, including research based on Twitter usage relating to pro and anti-mask and vaccine views; (00:40:41) conclusions drawn from the study on masks and vaccines, including findings relating to a response to political events, unifying concepts connecting groups together; (00:42:57) direct impact of these studies, including on minority ethnic communities, advice to policy-makers after working at a grass-roots level with these communities; (00:45:38) hesitancy amongst minorities, particularly due to past experiences and historical abuses, the importance of community groups having their voices heard; (00:48:14) new insights relating to vaccination views amongst the wider public, including controversies around side effects, high adoption of vaccines, COVAX and issues relating to manufacture and supply to low and middle-income countries; (00:51:32) the impact of vaccinations on global health, including lower mortality for infectious diseases; (00:53:36) the concept of lockdown fatigue; (00:55:54) the role of social sciences and humanities research towards the pandemic response; (00:56:43) future research interests, including the profile and portrayal of clinical trials in the media and public domain and how the structure and interest in trials have changed since COVID-19; (01:00:00) trial participants and other voluntary work within the community during the pandemic; (01:01:30) future trials and direct feedback from participant surveys; (01:02:28) SV's reaction to the threat of infection, particularly in relation to family members, personal experience of contracting COVID-19 and long COVID; (01:07:00) impact of COVID-19 on work, including remote work and working intensively; (01:07:47) involvement in teaching during the pandemic; (01:10:22) precautions within the Oxford Vaccine Group building; (01:14:55) research on COVID-19 and impact on SV's well-being; (01:17:21) changes to approach to work as a result of COVID-19.

Episode Information

Series
Collecting COVID: Oral Histories
People
Samantha Vanderslott
Georgina Ferry
Keywords
medical sciences
interdisciplinary research
communicable diseases
public health
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 02/11/2022
Duration:

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Professor Sandy Douglas (part two)

Series
Collecting COVID: Oral Histories
Embed
Georgina Ferry interviews Sandy Douglas, Associate Professor (Jenner Institute), 17 March 2022.
Topics discussed include (00:00:20) initial questions relating to the large-scale manufacturing of the vaccine, including early ideas relating to a University spin-out company, the decision to partner with AstraZeneca to manufacture and distribute the vaccine; (00:04:25) steps taken to implement the partnership with AstraZeneca, including the decision by John Bell in relation to establishing a partnership, equitable access, early communication with Merck and work with the Serum Institute of India and WuXi Biologics, priorities of the University; (00:09:55) major contribution of the Oxford-AstraZeneca vaccine, including the speed of delivery, willingness to partner so that commercial-scale manufacturing of the vaccine could be achieved; (00:15:25) communications with Halix, Pall Corporation and Cobra Biologics; (00:17:01) shipment of cells used to make the vaccine to the Serum Institute of India to expedite the process, negotiations between AstraZeneca and the Serum Institute of India and the granting of a sub-licence to the Serum Institute; (00:22:19) direct correspondence with AstraZeneca, including calls between the Oxford vaccine team and Pascal Soriot, other partnerships, vision and transfer of manufacture to various other sites; (00:27:39) changes made to the manufacturing process; (00:33:02) manufacture of the vaccine by AstraZeneca, including the extensive preparation, manufacture of the vaccine by smaller partners including Halix and Cobra Biologics; (00:37:27) use of the vaccine in early clinical trials; (00:42:50) up-scale of manufacturing process; (00:43:26) 'fill and finish' process; (00:46:40) clinical trial results in late 2020, the status of large-scale manufacturing of the vaccine at the end of 2020, tests required on the vaccine by various authorities and regulatory bodies; (00:52:30) responsibilities over the manufacturing process after summer 2020, work on improving the manufacturing process with the aim of making more vaccine; (00:55:20) tension between the speed of process and ensuring that quality was maintained; (00:57:47) the large-scale production of vaccine in early 2021, including the output at Oxford Biomedica, Halix and Cobra Biologics, global scarcity of vaccines, tension relating to the supply of the vaccine to the EU and other countries, AstraZeneca as a scapegoat; (01:02:16) trial data and dosage, single doses and protection; (01:04:58) January 2021 study on intranasal application of the vaccine, reports of blood clots occurring after vaccination.

Episode Information

Series
Collecting COVID: Oral Histories
People
Sandy Douglas
Georgina Ferry
Keywords
medical sciences
vaccines
astrazeneca (firm)
covid-19 (disease)
Department: Bodleian Libraries
Date Added: 02/11/2022
Duration: 01:11:07

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