Jamie Hartmann-Boyce and Nicola Lindson discuss emerging evidence in e-cigarette research and interview Jessica Yingst, Penn State Center for Research on Tobacco and Health, USA.
Associate Professor Jamie Hartmann-Boyce and Associate Professor Nicola Lindson discuss the new evidence in e-cigarette research and interview Dr Jessica Yingst. Dr Jessica Yingst is a member of the Penn State Center for Research on Tobacco and Health and is the co-director of the Career Enhancement Core with the Penn State Tobacco Center of Regulatory Science otherwise known as a TCORS. Jessica Yingst is a public health researcher focused on understanding methods to reduce harms associated with tobacco use.
In the June podcast Jessica Yingst shares the findings of their randomised clinical trial comparing standardized research e-cigarette (SREC) with 5% nicotine or 0%. Their study explored toxicant exposures after switching from cigarettes to a pod-based electronic cigarette. They wanted to determine the short-term effects of switching from cigarettes to a pod-based 5% nicotine e-cigarette, compared with a 0% nicotine e-cigarette. Their study found that participants who switched from cigarettes to a 5% nicotine SREC experienced reduced exposure to several tobacco-related toxicants and higher rates of cigarette abstinence than those who switched to a 0% nicotine SREC. Their findings suggest that e-cigarettes delivering nicotine at levels comparable to conventional cigarettes may play an important role in reducing exposure to harmful smoking-related toxicants while supporting complete smoking cessation.
This podcast is a companion to the electronic cigarettes Cochrane living systematic review and Interventions for quitting vaping review and shares the evidence from the monthly searches.
Our searches for the EC for smoking cessation review carried out on 1st June 2026 found: 3 new ongoing studies (NCT07039292, NCT07598136, NCT07199517) and 3 linked reports (10.1001/jamanetworkopen.2026.13292 (discussed in this podcast), 10.18332/tid/218987, 10.1111/add.70421).
Our search for our interventions for quitting vaping review carried out on 1st June 2026 found: 5 new ongoing studies (ACTRN12626000548336, NCT05037656, NCT07593742, 10.1186/s12889-026-27567-y, 10.1038/s41598-026-45720-w).
For further details see our webpage under 'Monthly search findings':
https://www.cebm.ox.ac.uk/research/electronic-cigarettes-for-smoking-cessation-cochrane-living-systematic-review-1
For more information on the full Cochrane review of E-cigarettes for smoking cessation updated in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010216.pub10/full
For more information on the full Cochrane review of Interventions for quitting vaping published in November 2025 see: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016058.pub3/full
