Skip to main content
Home

Main navigation

  • Home
  • Series
  • People
  • Depts & Colleges
  • Open Education

Main navigation

  • Home
  • Series
  • People
  • Depts & Colleges
  • Open Education

The Pandemic People: Prof. Eddie Holmes

Series
The Oxford Colloquy
Embed
Professor Eddie Holmes, who co-authored the publication of the genome sequence of SARS-CoV-2 through work with colleagues in Wuhan, China speaks to Professor Andrew Pollard about his scientific career and this pivotal pandemic work.
An interview between Prof Sir Andrew Pollard and Prof Eddie Holmes, an evolutionary biologist, fellow of the Academy of Sciences in Australia and the Royal Society. The discussion delves into the evolution of coronaviruses, with a particular focus on the origins of COVID-19 in Wuhan, China.  The interview begins by exploring Eddie's academic journey, from a background in social anthropology to his transition into the field of viruses and evolutionary genetics. The conversation highlights the rapid mutation rates of viruses, particularly viruses like HIV, which mutate daily in infected individuals. The episode develops further, discussing how Eddie found himself at the forefront of pandemic research, thanks to his previous work and collaborations in China. He explains the sequence of events leading to his involvement, from collaborating with researchers in Wuhan and Shanghai to the critical role in identifying the virus responsible for the outbreak and sharing this information internationally.
 
The conversation then explores the role of mutation tracking in determining the cross-species transmission of viruses, such as COVID-19, which allows scientists to trace the origins of a virus and determine potential reservoir species. Eddie provides insights into the origins of SARS-CoV-2 through natural mutation between species, and highlights the challenges and criticisms faced by scientists involved in the investigation.
 
The discussion also explores how the environment, which includes factors like drugs, vaccines, and the host's immune response, influences the mutations in viruses. Eddie explains that the environment acts as a selective sieve, allowing certain mutations to survive and shaping the evolution of the virus. Regarding the long-term control of highly mutable viruses, such as HIV and SARS-CoV-2, Eddie suggests that while predicting and targeting the right mutations is challenging, it is not impossible. He discusses the potential for AI to improve prediction and intervention strategies. However, the ongoing evolution of viruses and the need to adapt drugs and vaccines to new variants remain challenges to be addressed. The podcast provides valuable insights into the fascinating world of viral evolution, offering a glimpse into the complexities of viruses and their impact on human health.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
The Oxford Colloquy
People
Andrew Pollard
Eddie Holmes
Keywords
evolutionary biologist
coronaviruses
SARS-CoV-2
 COVID-19
 COVID-19 origins
SARS-CoV-2 origins
social anthropology
evolutionary genetics
mutation rates
hiv
vaccines
antiviral drugs
virus mutations
cross-species transmission
reservoir species
environmental factors
virus evolution
ai
intervention strategies
viral evolution
human health
Department: Department of Paediatrics
Date Added: 30/10/2023
Duration: 00:39:40

Subscribe

Download

Pervez Hoodhboy

No podcasts episodes were found for this contributor.

Pakistan & India: Common Origins, Divergent Trajectories

Series
Asian Studies Centre
Embed
Pervez Hoodbhoy seminar given as part of the Modern South Asian Seminar series in October 2023
What had been a relatively small gap in 1947 between Pakistan and India is turning into an ever widening chasm. Given the common origins of these two countries what essential differences led to the present situation? Or were the trajectories predetermined? After discussing historical similarities and differences, I will explore whether Pakistan can now choose a different future for itself.

Pervez Hoodbhoy taught physics at Quaid-e-Azam University in Islamabad (1973–2021) as well as other Pakistani universities for nearly five decades. He was visiting professor at MIT, Carnegie Mellon University, and the University of Maryland, and a post-doctoral research fellow at the University of Washington. His book “Islam and Science – Religious Orthodoxy and the Battle for Rationality” was translated into 8 languages.

Episode Information

Series
Asian Studies Centre
People
Pervez Hoodbhoy
Keywords
india
South Asia
Pakistan
history
Department: St Antony's College
Date Added: 26/10/2023
Duration: 00:31:11

Subscribe

Download

Valeria Colunga Lozano

No podcasts episodes were found for this contributor.

Valeria Colunga Lozano

Series
The Provcast
Embed
Meet a Weidenfeld-Hoffmann Trust scholar.
Valeria Colunga Lozano has recently completed her MSc in Global Governance and Diplomacy as a Weidenfeld-Hoffmann Trust scholar at Worcester College. She chats to David about her research into inter-generational justice, environmental activism and the damage caused by short-termism. She also tells us about her experience as a Mexican delegate at the G20 youth forum (Y20 India 2023) and why she's optimistic about the future.

Episode Information

Series
The Provcast
People
David Isaac
Valeria Colunga Lozano
Keywords
provcast
interview
Worcester
Department: Worcester College
Date Added: 16/10/2023
Duration: 00:28:25

Subscribe

Download

S2 Ep1: BOOKNESS with Paul Johnson

Series
BOOKNESS at the Bodleian Library
Embed
BOOKNESS talks to book artist Paul Johnson about his pop-up book ‘Dies Natalis’, which was created as a gift to the Bodleian library for the Gifts and Books exhibition.
Images of this week's book are at: https://blogs.bodleian.ox.ac.uk/theconveyor/category/BOOKNESS/

Episode Information

Series
BOOKNESS at the Bodleian Library
People
Alice Evans
Jo Maddocks
Paul Johnson
Keywords
artists’ books
bodleian
special collections
pop-up
moveables
Department: Bodleian Library
Date Added: 13/10/2023
Duration: 00:29:10

Subscribe

Download

Paulo Nadanovsky

No podcasts episodes were found for this contributor.

Evidence-based dentistry: The building of the Dental Fact Box repository – OHA!

Series
Evidence-Based Health Care
Embed
An introduction to OHA!, a tool currently being developed which aims to assist dentists in accessing the most reliable evidence regarding the effectiveness of common dental treatments.
The OHA! repository has been purposefully crafted to be exceptionally selective and compact, ensuring that users can easily find straightforward and valuable answers to their dental clinical questions. During the presentation, Professor Paulo Nadanovsky will show two sample dental fact boxes (in draft form) that have been developed. One pertains to the success rate of root canal treatment, while the other focuses on the impact of shorter versus longer intervals between dental check-ups on oral health. Patients expect doctors to take action to help them, and the more treatment or diagnostic tests, the better they feel. Doctors genuinely want to help and can often come up with various treatment or testing options to try. Consequently, this leads to a situation where everyone becomes perpetual patients, regardless of their actual health needs and potential benefits – essentially, an overuse of healthcare. Furthermore, there is a pervasive illusion of certainty among healthcare professionals, including physicians and dentists. This illusion entails the belief that treatments are always effective, diagnostic tests are infallible, and there exists only a single, optimal treatment or management approach. Consequently, there is often a lack of systematic comparisons between the pros and cons of different options. To dispel this illusion of certainty, reduce excessive healthcare practices, and promote clear thinking when considering interventions, the provision of clear information is essential. The practice of evidence-based healthcare involves two distinct roles: that of evidence consumers and evidence producers. Consumers, including clinicians and the general public, often lack the expertise needed to evaluate and choose the most reliable evidence. Hence, it falls upon those producing healthcare evidence to assume the role of experts and develop tools that simplify the integration of the best available evidence into the decision-making process for clinicians and patients alike.

Bio: Professor Nadanovsky graduated as a dentist in Rio de Janeiro, Brazil. He worked for a few years in the clinic (mainly periodontics), then migrated to public health and epidemiology and obtained a PhD from the University of London in 1993. He witnessed the birth of the evidence-based medicine movement and of the Cochrane Collaboration while working as a lecturer at the London Hospital Medical College and at University College London (afterwards it was renamed Queen Mary and Westfield College). Professor Nadanovsky taught evidence-based dentistry between 1993 and 1997 and since 1997 has been teaching epidemiology and evidence-based health care to physicians, dentists, nutritionists, and other health care professionals. He supervises PhD and MSc students, and his main interest is in overdiagnosis and overtreatment in health care in general, and more specifically, in dentistry.

Episode Information

Series
Evidence-Based Health Care
People
Paulo Nadanovsky
Keywords
EMB
Evidence-Based Medicine
Primary Care
Health Sciences
EBHC
Evidence-Based Health Care
qualitative research methods
Department: Medical Sciences Division
Date Added: 12/10/2023
Duration: 00:53:08

Subscribe

Download

Rebecca Donner

No podcasts episodes were found for this contributor.

Jud Newborn

No podcasts episodes were found for this contributor.

Pagination

  • First page
  • Previous page
  • …
  • Page 128
  • Page 129
  • Page 130
  • Page 131
  • Page 132
  • Page 133
  • Page 134
  • Page 135
  • Page 136
  • …
  • Next page
  • Last page

Footer

  • About
  • Accessibility
  • Contribute
  • Copyright
  • Contact
  • Privacy
  • Login
'Oxford Podcasts' X Account @oxfordpodcasts | Upcoming Talks in Oxford | © 2011-2026 The University of Oxford