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Practical Uses of NMR: Exploring Enzymes to Fight Disease

Series
Chemistry for the Future: Human Health
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The mutant enzymes that cause disease in our bodies can be combated by chemical inhibitors if we understand how these molecules are interacting.
Dr Ivanhoe Leung shows how Nuclear Magnetic Resonance (NMR) can be used to study enzymes in three critical ways.

Episode Information

Series
Chemistry for the Future: Human Health
People
Ivanhoe Leung
Keywords
NMR
enzymes
disease
inhibitors
nuclear magnetic resonance
Health
mutation
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:04:51

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Lasers, Cell Membranes, and the Basis of Life

Series
Chemistry for the Future: Human Health
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Being a chemist doesn't have to mean giving up on biology and physics.
Dr Mark Wallace and postdoc Dr Matt Baker use lasers, fluorescent tagging, and other interdisciplinary techniques to study cell membrane interactions and better understand their function in infection and disease.

Episode Information

Series
Chemistry for the Future: Human Health
People
Mark Wallace
Matt Baker
Keywords
biology
cells
TATA
infection
Health
lasers
maths
cell membranes
chemistry
Physics
bilayer
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:05:20

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Synthesizing Anti-Cancer Drugs from Nature

Series
Chemistry for the Future: Human Health
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Chemicals found in nature can have incredibly useful functionality, including anti-malarial and anti-cancer properties. However, they are usually found in small amounts.
Chris Jones, a DPhil student in the Donohoe Group, is synthesizing naturally occurring molecules in the lab so they can be used as drugs on a larger scale.

Episode Information

Series
Chemistry for the Future: Human Health
People
Chris Jones
Keywords
biology
malaria
cancer
science
disease
Health
Medicine
gin
drug discovery
nitrogen heterocycles
synthesis
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:06:59

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3D Printing and The Structure of Proteins

Series
Chemistry for the Future: Human Health
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Using 3D printed molecules, Rok Sekirnik, a DPhil student in the emerging field of chemical biology, shows how protein structures can be determined in some of the Department's most distinctive looking labs.

Episode Information

Series
Chemistry for the Future: Human Health
People
Rok Sekirnik
Keywords
biology
3D printing
drugs
science
genes
proteins
disease
Health
chemical biology
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:08:43

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Epigenetics and New Anti-Cancer Treatments

Series
Chemistry for the Future: Human Health
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At the interface of chemistry, biology, and medicine, Cyrille Thinnes, a DPhil student in the Schofield Group, shares his research into the next generation of anti-cancer treatments.

Episode Information

Series
Chemistry for the Future: Human Health
People
Cyrille Thinnes
Keywords
biology
oncogenes
cancer
science
genes
proteins
disease
oncology
Health
treatment
Medicine
DNA
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:08:36

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Introduction: How Chemistry Research Impacts Human Health

Series
Chemistry for the Future: Human Health
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To truly understand disease, we need to understand the underlying chemical processes that direct human biology. Dr Emily Flashman introduces some of the research in the Department of Chemistry that will help improve our health in future.

Episode Information

Series
Chemistry for the Future: Human Health
People
Emily Flashman
Keywords
biology
cancer
science
genes
proteins
disease
Health
women in science
Medicine
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:02:27

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Chemistry for the Future: Human Health

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Chemistry for the Future: Human Health
It was here in Oxford, in the 1600s, that great minds such as Hooke, Boyle, Willis and Wren laid the foundations of modern experimental science. Like their famous forebears, today's Oxford scientists continue to undertake world-leading research: making fundamental new discoveries and applying cutting-edge knowledge to the major societal and technological challenges of the day. The research happening right now in the Department of Chemistry is uniquely poised to have a major impact on everything from our health to our energy sources - in other words, it is enabling our shared future. To read more about our research, please visit http://www.chem.ox.ac.uk/researchthemes.asp.
This series explores the interdisciplinary interface between chemistry and human health. From using lasers to study cell membranes, to synthesizing anti-cancer drugs, the research explored in these podcasts will help us to be healthier and happier in future.

For more information regarding the science discussed in these podcasts, please visit the following websites:
Donohoe Group: http://donohoe.chem.ox.ac.uk/
Dr Emily Flashman: http://research.chem.ox.ac.uk/emily-flashman.aspx
Schofield Group: http://www.chem.ox.ac.uk/oc/cjschofield/
Wallace Group: http://wallace.chem.ox.ac.uk/
NMR: http://www.chem.ox.ac.uk/spectroscopy/nmr/
Synthesis: http://oxsync.chem.ox.ac.uk/

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Conclusion: Inspired by Nature

Series
Chemistry for the Future: Solar Fuels
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The current energy crisis is a time of intense challenges but also of opportunities for fantastic science and innovative ideas.
Chemists, along with partners in other scientific disciplines, in policy, in industry, in advocacy, and beyond, all have a crucial role to play. Do you have any bright ideas?

Episode Information

Series
Chemistry for the Future: Solar Fuels
People
Alex T. Vai
Keywords
Energy
research
sustainable
future
fuel
technology
solar power
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:02:20

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Artificial Photosynthesis - From Photon to Fuel

Series
Chemistry for the Future: Solar Fuels
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Andrea Bachmeier, a DPhil student in the Armstrong Group, is helping to create a fully integrated artificial photosynthesis (APS) system which could be much more efficient at turning sunlight into fuel than living systems.

Episode Information

Series
Chemistry for the Future: Solar Fuels
People
Andreas Bachmeier
Keywords
solar fuels
sun
Energy
sustainable
artificial photosynthesis
fuel
solar power
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:12:53

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Photosynthesis in Nature

Series
Chemistry for the Future: Solar Fuels
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Dr Alison Foster, a former chemist and Senior Curator at the University of Oxford Botanic Garden explains the principals of natural photosynthesis that the Armstrong Group is trying to mimic in the lab.

Episode Information

Series
Chemistry for the Future: Solar Fuels
People
Alison Foster
Keywords
Solar energy
chlorophyll
nature
green plants
sunlight
solar
University of Oxford Botanic Garden
sun
Photosynthesis
Department: Department of Chemistry
Date Added: 19/07/2013
Duration: 00:04:00

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