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Lowering cholesterol in chronic kidney disease

Series
Translational Medicine
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The largest trial investigating the benefits of cholesterol lowering in kidney patients.
The Study of Heart and Renal Protection (SHARP) concluded that around a quarter of all heart attacks, strokes, and operations to open blocked arteries could be avoided in people with chronic kidney disease by using the combination of ezetimibe and simvastatin to lower blood cholesterol levels.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Colin Baigent
Keywords
Epidemiology
meta-analysis
clinical trials
cardiovascular disease
Department: Nuffield Department of Clinical Medicine
Date Added: 03/04/2012
Duration: 00:05:44

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Hepatitis C vaccine

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Translational Medicine
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Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine.
Dr Ellie Barnes aims to develop a prophylactic and a therapeutic hepatitis C virus vaccine to combat a global epidemic currently infecting 170 million people worldwide. Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer, liver cirrhosis and liver failure.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Ellie Barnes
Keywords
therapy
Hepatitis C virus
T cells
vaccine
genotype-3
Department: Nuffield Department of Clinical Medicine
Date Added: 03/04/2012
Duration: 00:05:08

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Hepatitis C vaccine

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Epidemics and Vaccines
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Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine.
Hepatitis C virus is a global epidemic, affecting around 200 million people worldwide. Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer, liver cirrhosis and liver failure. Unlike other vaccines, inducing antibody reactions to Hepatitis C is often ineffective because antibodies only target the outer surface of the virus. To combat this Dr Ellie Barnes is developing a new therapeutic vaccine for this damaging virus.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Epidemics and Vaccines
People
Ellie Barnes
Keywords
therapy
Hepatitis C virus
T cells
vaccine
genotype-3
Department: Nuffield Department of Clinical Medicine
Date Added: 03/04/2012
Duration: 00:05:08

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Facebook, Privacy and You

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Free Speech Debate
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Is the age of privacy over? Lord (Richard) Allan from Facebook and Viktor Mayer-Schönberger, author of Delete, go head to head on privacy and the right to be forgotten in the internet era.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Free Speech Debate
People
Richard Allan
Viktor Mayer-Schonberger
Timothy Garton Ash
Keywords
Google
privacy
free speech
wikipedia
Collection
facebook
policy
china
data
delete
Department: St Antony's College
Date Added: 30/03/2012
Duration: 01:38:28

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Exploring the demographic transition in the 21st Century

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Is the planet full? Seminar Series 2011
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Many countries around the world are experiencing a demographic transition that is occurring due to increased longevity combined with low fertility rates.
However, demographic momentum means that the global population is expected to continue to increase until at least the middle of the century, likely peaking near 10 billion.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Is the planet full? Seminar Series 2011
People
Sarah Harper
Keywords
oxfordmartin
growth
population
Department: Oxford Martin School
Date Added: 29/03/2012
Duration: 00:48:57

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An introduction to the ebook - 'Geographies of the World's Knowledge'

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Geographies of the World's Knowledge
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Dr Mark Graham introduces 'Geographies of the World's Knowledge'. The book, available as PDF and interactive iBook, visualizes and explores contemporary patterns of commercially produced and peer-produced knowledge.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Geographies of the World's Knowledge
People
Mark Graham
Keywords
society
data
visualization
internet
Department: Oxford Internet Institute
Date Added: 28/03/2012
Duration: 00:06:01

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Geographies of the World's Knowledge

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Geographies of the World's Knowledge
Who owns the world's knowledge? Who produces it? Who is able to consume it? Has the Internet democratized geographies of information? This free interactive book containing accessible, informative and beautiful maps and graphics illustrates geographies of knowledge in our Internet Age. It visualizes and explores contemporary patterns of commercially produced and peer-produced knowledge. The intriguing results should be seen by anyone interested in better understanding the global flows of knowledge.

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Webometrics: The Evolution of a Digital Social Science Research Field

Series
Oxford Internet Institute - Lectures and Seminars
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Mike Thelwall's Keynote talk from the OII Symposium "Social Science and Digital Research: Interdisciplinary Insights", March 2012.
This is a Keynote talk from the Oxford Internet Institute's Symposium "Social Science and Digital Research: Interdisciplinary Insights", held in Oxford on 12 March 2012. The research field of webometrics encompasses various forms of web-based link and text analyses. Webometric studies have included large scale analyses of social network sites and social web sites like Flickr, Twitter and YouTube, as well as areas of the traditional web, such as university websites. Webometrics began in 1997 within the discipline of Library and Information Science (LIS) in response to the recognition that commercial search engines could turn the Web into a large database for certain types of LIS research. In response to technical challenges involving automatically gathering web data, webometrics attracted people with computing backgrounds and became an interdisciplinary field in approximately 2000. Webometrics further evolved in 2003, when it began to incorporate social science research goals outside of LIS. The evolution was cemented in 2008 with the development of information-centred research theory: defining a type of research that had the goal of discovering suitable social science applications for new types of web information (Thelwall, Wouters and Fry, 2008). Since then webometrics has consciously attempted to develop quantitative web research methods and theories to have general application within social science, although continuing to prioritise LIS goals and approaches. This talk evaluates the impact and progress of webometrics: its impact within LIS and the wider social sciences. Although webometrics has been repeatedly singled out for its achievements within LIS, outside of LIS it has been much less successful. The evaluation will centre on evidence for the uptake of the methods generated by practicing webometricians and reasons behind their successes and failures.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Oxford Internet Institute - Lectures and Seminars
People
Mike Thelwall
Keywords
social media
link analysis
knowledge
information
internet
science
digital
text analysis
research
social
policy
webmetrics
technology
web data
social science
Department: Oxford Internet Institute
Date Added: 28/03/2012
Duration: 00:22:17

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Visioning Studies: A Socio-technical Approach to Designing the Future

Series
Oxford Internet Institute - Lectures and Seminars
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Diane H. Sonnenwald's Keynote talk from the OII Symposium "Social Science and Digital Research: Interdisciplinary Insights", March 2012.
This is a Keynote talk from the Oxford Internet Institute's Symposium "Social Science and Digital Research: Interdisciplinary Insights", held in Oxford on 12 March 2012. It is increasingly important to understand the potential impact of future technology in complex contexts as early as possible in the research and development (R&D) cycle. Understanding the potential impact, including its interaction with social structures, helps inform funding and research decisions. It identifies technology capabilities that may enhance the technology's adoption and use, and reduce its unintended negative consequences. It also uncovers potential conflicts with current social structures, facilitating the identification of enhancements to social structures and/or practices to derive benefit from the technology. To understand the potential impact of future technology we have been developing a research approach called "visioning studies". The goal of a visioning study is to understand the perspectives of potential users and stakeholders, and from this understanding develop socio-technical design recommendations in collaboration with computer science researchers and relevant stakeholders. We have explored two visioning study approaches: a mixed method approach involving simulation, surveys and interviews; and a semi-structured approach in which a video depicting the technology vision embedded in relevant realistic scenarios is used in conjunction with semi-structured interviews. To date, visioning studies have been conducted regarding 3D telepresence technology in emergency health care and mobile technology in policing.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Oxford Internet Institute - Lectures and Seminars
People
Diane H. Sonnenwald
Keywords
knowledge
internet
science
digital
research
social
policy
technology
social science
Department: Oxford Internet Institute
Date Added: 28/03/2012
Duration: 00:23:27

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Reproducibility: Gold or Fool's Gold in Digital Social Research?

Series
Oxford Internet Institute - Lectures and Seminars
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Christine Borgman's Keynote talk from the OII Symposium "Social Science and Digital Research: Interdisciplinary Insights", March 2012.
This is a Keynote talk from the Oxford Internet Institute's Symposium "Social Science and Digital Research: Interdisciplinary Insights", held in Oxford on 12 March 2012. Data sharing has become a core tenet of science policy in the UK, the US, and elsewhere. Among the rationales for sharing data is improving the ability to reproduce or to replicate research. Reproducibility is an oft-stated "gold standard" for science, yet it is a problematic rationale for sharing research data. Sociologists of science have described the difficulties of verifying, let alone reproducing, scientific results, since the 1970s. While most sciences are experiencing a data deluge, the characteristics and practices associated with data vary widely, with different requirements for replication. Reproducibility concerns underlie peer review, identification of fraud, bio-security, and publication practices. The role of data in reproducing science lies at the intersection of e-Science, practice, and policy, and thus is a significant problem to be addressed by digital social research.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Oxford Internet Institute - Lectures and Seminars
People
Christine Borgman
Keywords
data sharing
bibliometrics
knowledge
internet
science
digital
research
data deluge
computer science
social
policy
social science
Department: Oxford Internet Institute
Date Added: 28/03/2012
Duration: 00:19:11

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