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Keith Gull

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews Keith Gull.
Keith Gull FRS is the Principal of St Edmund Hall, Oxford, and Professor of Molecular Microbiology. He studied microbiology at Queen Elizabeth College in London and remained there to do a PhD, moving straight into a lectureship at the University of Kent in 1972. There he used electron microscopy to study microtubules, first in fungi and later in disease-causing microbes, the trypanosomes. Gull moved to the University of Manchester in 1989 as Professor of Biochemistry, and participated in the restructuring of its School of Biological Sciences. Deciding to focus on science rather than administration, he won a Wellcome Trust Principal Fellowship, which enabled him in 2002 to move into the newly-completed EP Abraham Research Building at the Dunn School. His group explored the proteins that make up the flagella of microbes, conserved in evolution to form the cilia of mammalian cells. He has helped to reorganise graduate education in Medical Sciences at Oxford, and set up collaborations to improve the training of young scientists in Africa. Unusually, since becoming Head of House at St Edmund Hall in 2009 he has continued to lead an active research lab in the Dunn School.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
Keith Gull
Keywords
oral history
pathology
history
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 01:53:06

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Gillian Griffiths

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews Gillian Griffiths.
Gillian Griffiths FRS is Professor of Immunology and Cell Biology and Director of the Cambridge Institute for Medical Research at the University of Cambridge. While an undergraduate at University College London she was encouraged by immunologists Martin Raff and Avrion Mitchison to apply for a PhD with César Milstein at the MRC Laboratory of Molecular Biology in Cambridge. Under Milstein’s guidance she was the first to sequence the complete variable regions of antibodies. She then spent five years as a post-doc at Stanford University in California before moving to the Basel Institute of Immunology in 1990 to work on the cell biology of killer T cells. In 1995 she won a Wellcome Trust Senior Fellowship and two years later came to the Dunn School to set up her lab. Her work revealed the mechanisms by which killer cells neutralise infected or cancerous cells with exquisite precision. In 2001 she was given the title of Professor, the first woman to hold such a title in the department. She moved to Cambridge for family reasons in 2008.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
Gillian Griffiths
Keywords
pathology
oral history
history
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 01:35:59

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David Greaves

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews David Greaves.
David Greaves is Professor of Inflammation Biology at the Dunn School. He did a first degree in microbiology and biochemistry at the University of Bristol before going to King’s College, London for his PhD. He worked on the expression of the beta globin gene in the same laboratory where Maurice Wilkins and Rosalind Franklin had carried out their studies of the structure of DNA. A first post-doctoral position took him to Amsterdam to work on gene expression in trypanosomes. He returned to the UK to join the National Institute for Medical Research at Mill Hill before briefly working in the laboratories of GD Searle Monsanto. His return to academic research in 1993 came in the form of a post-doctoral position with Siamon Gordon at the Dunn School, using transgenic models to study the role of macrophages in inflammation. Since 1999 he has continued this work as a group leader, also developing the use of live-cell imaging to study the process of phagocytosis. Since the early 2000s Greaves has been responsible for organising the teaching of pathology and microbiology to up to 150 medical students per year.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
David Greaves
Keywords
history
pathology
oral history
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 00:55:23

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Matthew Freeman

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews Matthew Freeman.
Matthew Freeman FRS joined the Dunn School as Professor of Pathology and head of department in 2013. He remembers meeting the Nobel-prizewinning immunologist Peter Medawar as a teenager, who told him 'Chemistry is dead, Physics is dying and Biology is the only science that’s worth pursuing.' Inspired by this, Freeman read Biochemistry at Oxford before going to Imperial College London to undertake a PhD in on the genetic control of the cell cycle in fruit flies, in a department that was one of the first to use recombinant DNA methods to clone genes. This led to a post-doc at the University of California at Berkeley, from which he returned in 1992 to set up his own lab at the MRC Laboratory of Molecular Biology in Cambridge, working on receptors that are critical to the development of the Drosophila eye. He remained at LMB for 21 years, for the last six as head of the Cell Biology Division. Since his move to head the Dunn School he has focused on encouraging collaboration between research groups, under an over-arching definition of pathology as ‘the cell biology that underlies human disease’. He is a trustee of the EP Abraham Research Fund.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
Matthew Freeman
Keywords
history
pathology
oral history
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 01:22:42

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Paul Fairchild

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews Paul Fairchild.
Paul Fairchild is Associate Professor and Lecturer in Medicine at the Dunn School and was Co-Director of the Oxford Stem Cell Institute from 2008-2015. He first came to Oxford in 1987 to undertake a DPhil in the Nuffield Department of Surgery, working with Jonathan Austyn who had been a student in the Dunn School with Siamon Gordon. Fairchild worked on the role of dendritic cells in preventing autoimmunity through the induction of tolerance in T cells. He then went to the Department of Pathology at Cambridge for post-doctoral research on how this system fails in multiple sclerosis. There he met Hermann Waldmann: when Waldmann succeeded Henry Harris as head of the Dunn School he invited Fairchild to join his group in Oxford. Fairchild developed a technique for differentiating embryonic stem cells into dendritic cells. In 2008 he became the founding director of the Oxford Stem Cell Institute, which brings together 50 laboratories in 17 departments across the university, in collaborative projects initially supported by the Oxford Martin School. He has also been editor of the Dunn School magazine, Fusion, for ten years.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
Paul Fairchild
Keywords
history
oral histories
pathology
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 00:49:09

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Peter Cook

Series
Sir William Dunn School of Pathology Oral Histories
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Georgina Ferry interviews Peter Cook as part of the
Peter Cook has retired from his post as Professor of Cell Biology, but continues to pursue his research half-time in the Dunn School as a departmental lecturer. He read Biochemistry as an undergraduate at Oxford, and moved to the Dunn School in 1967 to pursue research for a DPhil under the supervision of the head of department, Henry Harris. He has remained in the department ever since. Cook’s research as a graduate student used cell fusion to study how gene expression was controlled. His subsequent research has focused on the structural basis of transcription, looking at the coiling and folding of DNA in chromosomes and the interaction of the genetic material with enzymes. Working with a colleague in Engineering Science, he has set up a company called iotaSciences to develop an invention that can handle very small volumes of liquids for purposes such as biological experimentation. He is a Trustee of the Guy Newton Research Fund and chairs the CIU Trust set up by Neil Barclay.

Episode Information

Series
Sir William Dunn School of Pathology Oral Histories
People
Georgina Ferry
Peter Cook
Keywords
history
pathology
oral histories
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 01:35:01

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Sir William Dunn School of Pathology Oral Histories

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Thumbnail image with Oxford University branding with icons of a cell and machine networks, with the title "Immunity by Design - from Cells to Systems Through Human and Machine Intelligence
In 2017, as part of the '75 Years of Penicillin in People' project funded by the Wellcome Trust, the Bodleian Libraries commissioned a series of oral history interviews with scientists, administrators, and technicians who work, or formerly worked, at the University of Oxford's Sir William Dunn School of Pathology. The interviews were conducted by Georgina Ferry.

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History of Art - The De Spira Brothers vrs. Nicolaus Jenson, 1469-1472: A Rivalry Traced through Hand-illuminated Copies of their Editions

Series
History of the Book 2017-2019
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Professor Lilian Armstrong (Wellesley College) gives a talk for the History of the Book seminar series on 2nd March 2018.

Episode Information

Series
History of the Book 2017-2019
People
Lilian Armstrong
Keywords
books
history
art history
book trade
Department: Bodleian Libraries
Date Added: 06/03/2018
Duration: 00:53:29

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How to ask the right questions: Lessons learned in 30 years of research

Series
Surgical Grand Rounds Lectures
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Professor Wytske Fokkens (Department of Otorhinolaryngology, Academic Medical Center, Amsterdam) talks about how to ask yourself the right questions, which is the most important thing that she has learned in her 30-year research career.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Surgical Grand Rounds Lectures
People
Wytske Fokkens
Keywords
surgery
surgeons
research
academic
Medicine
questions
career
Department: Nuffield Department of Surgical Sciences
Date Added: 05/03/2018
Duration: 00:44:45

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FMR 57 - From the editors

Series
Syrians in displacement (Forced Migration Review 57)
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This issue therefore focuses – as did the 2014 issue – on displacement from and within Syria.

Episode Information

Series
Syrians in displacement (Forced Migration Review 57)
People
Marion Couldrey
Jenny Peebles
Keywords
fmr
forced migration review
refugee
forced migrant
asylum seeker
asylum
syrian refugees
Department: Refugee Studies Centre
Date Added: 05/03/2018
Duration: 00:03:41

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