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Biological imaging

Series
Translational Medicine
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Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data.
Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and the Department of Engineering Science. His research aims to enhance our understanding of complex biological processes through the analysis of image data acquired at the microscopic scale.

Episode Information

Series
Translational Medicine
People
Jens Rittscher
Keywords
microscopy
target discovery
drug development
data
biological processes
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:07:25

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Pharmacogenomics

Series
Translational Medicine
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Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions.
In the context of cancer, genetic diversity means that we respond differently to various treatments. Pharmacogenomics sits at the intersection between genetics and drugs. Better understanding of the genetic landscape of cancer and the recent increase of targeted drugs allow us to better match patients with the best treatments, improving care.

Episode Information

Series
Translational Medicine
People
Sebastian Nijman
Keywords
pharmacogenomics
signalling networks
cancer cells
genetics
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:04:27

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Biological imaging

Series
Translational and Clinical
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Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data.
Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and the Department of Engineering Science. His research aims to enhance our understanding of complex biological processes through the analysis of image data acquired at the microscopic scale.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Jens Rittscher
Keywords
microscopy
target discovery
drug development
data
biological processes
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:07:25

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Personalised Medicine

Series
Cancer
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Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions.
Clinical diagnoses can be broad descriptions, but today's test results can help better understand the condition as well as target treatment. Cancer is a good example in which personalised medicine can help decide which molecular targeted therapy is most appropriate.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Jenny Taylor
Keywords
genetics
diagnosis
treatment
clinical
personalised
targeted
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:04:09

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Cancer predisposition and evolution

Series
Cancer
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Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stage. A better understanding of how and why cancers grow also helps develop improved treatments.
Ian Tomlinson, Professor of Molecular and Population Genetics at the Wellcome Trust for Human Genetics, works on the identification of genes that predispose to colorectal and other cancers. His research focuses on the relative importance of selection and genomic instability.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Ian Tomlinson
Keywords
genes
predispose
cancer
genomic instability
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:03:45

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Cancer Informatics

Series
Cancer
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Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of this variability at molecular level will help us better tailor treatments to individual cancer patients.
Dr Benjamin Schuster-Böckler heads the computational group at the Ludwig Institute for Cancer Research. His work has demonstrated that epigenetic modifications influence the mutational landscape in cancer cells. He studies the effects of DNA-binding proteins on transcription factors, with the aim to understand the regulation (and mis-regulation) of the transcription of important oncogenes and tumour suppressors.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Benjamin Schuster-Böckler
Keywords
cancer
data
computational
epigenetic
dna binding proteins
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:06:01

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Pharmacogenomics

Series
Translational and Clinical
Embed
Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions.
In the context of cancer, genetic diversity means that we respond differently to various treatments. Pharmacogenomics sits at the intersection between genetics and drugs. Better understanding of the genetic landscape of cancer and the recent increase of targeted drugs allow us to better match patients with the best treatments, improving care.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Sebastian Nijman
Keywords
pharmacogenomics
signalling networks
cancer cells
genetics
Department: Nuffield Department of Clinical Medicine
Date Added: 09/02/2015
Duration: 00:04:27

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The top five dilemmas of news aggregation

Series
Reuters Institute for the Study of Journalism
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Andrew Jack, Editor at FirstFT, head of aggregation/chief curator, gives a talk for the Reuters Institute seminar series on 4th February 2015.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Reuters Institute for the Study of Journalism
People
Andrew Jack
Keywords
politics
news
journalism
news aggregation
Department: Department of Politics and International Relations (DPIR)
Date Added: 09/02/2015
Duration: 00:22:55

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Skeptical Theism and the Future

Series
Religious Epistemology, Contextualism, and Pragmatic Encroachment
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First talk given by Cameron Domenico Kirk-Giannini (Rutgers) at the New Insights and Directions for Religious Epistemology Workshop on Formal Epistemology and Religious Epistemology, Oxford University, 8 December 2014.

Episode Information

Series
Religious Epistemology, Contextualism, and Pragmatic Encroachment
People
Cameron Domenico Kirk-Giannini
Keywords
philosophy
religious epistemology
religion
epistemology
Department: Faculty of Philosophy
Date Added: 09/02/2015
Duration: 01:17:40

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Foundations for an Accuracy-based Approach to Imprecise Credence

Series
Religious Epistemology, Contextualism, and Pragmatic Encroachment
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Second talk given by Jason Konek (Bristol) and Billy Dunaway (Oxford) at the New Insights and Directions for Religious Epistemology Workshop on Formal Epistemology and Religious Epistemology, Oxford University, 8 December 2014.

Episode Information

Series
Religious Epistemology, Contextualism, and Pragmatic Encroachment
People
Jason Konek
Billy Dunaway
Keywords
philosophy
religious epistemology
religion
epistemology
Department: Faculty of Philosophy
Date Added: 09/02/2015
Duration: 01:30:30

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