SHARP

Series

Embed

Lowering cholesterol in chronic kidney disease

The Study of Heart and Renal Protection (SHARP) concluded that around a quarter of all heart attacks, strokes, and operations to open blocked arteries could be avoided in people with chronic kidney disease by using the combination of ezetimibe and simvastatin to lower blood cholesterol levels.

The SHARP study involved almost 9,500 volunteers aged 40 or over with chronic kidney disease recruited from 380 hospitals in 18 countries. Volunteers were randomly allocated to take either cholesterol-lowering therapy with a tablet containing ezetimibe 10mg daily and simvastatin 20mg daily, or matching dummy "placebo" tablets for an average of 5 years.

Episode Information

Series

Translational and Clinical

People

Keywords

cardiovascular disease

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 00:05:44

Download

Wider Statin Use Saves Lives

Series

Translational and Clinical

Embed

Wider Statin Use Saves Lives

The largest and most reliable study ever to examine the effect of statins has found them to reduce the risk of heart attacks, strokes and premature deaths among a wide range of apparently healthy people. The benefits greatly exceed any known risks associated with taking these drugs.

Episode Information

Series

Translational and Clinical

People

Keywords

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 00:05:56

Download

Better hospitals for children

Series

Translational Medicine

Embed

Oxford Health Systems Research Collaboration (OHSCAR)

Professor Mike English leads the Health Services Unit at the KEMRI-Wellcome Trust Research Programme in Nairobi, Kenya. This unit aims to strengthen equality in access to affordable quality health care in Africa. Studies are based on health systems clustered around five main topics: malaria, service delivery & access, information for decision making, governance and financing.

Professor English leads efforts to develop multidisciplinary links with Oxford through the Oxford Health Systems Research Collaboration (OHSCAR).

Creative Commons Licence

Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series

Translational Medicine

People

Keywords

health systems research

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 04:23:00

Download

Health systems research

Series

Translational Medicine

Embed

Governance in practice

Dr Sassy Molyneux's main interests reside in Social science and Ethics in Public Health. Over the years, social scientists have developed a programme of empirical work on research ethics. This work is based on an understanding that while the ethics of human subjects research may be universal, there can be big differences across contexts and circumstances in key ethical issues or principles.

Creative Commons Licence

Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series

Translational Medicine

People

Sassy Molyneux

Keywords

sassy molyneux

health systems research

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 07:11:00

Download

The Crisis of the Meritocracy: Education and Democracy in Modern Britain

Series

St Edmund Hall

Embed

Professor Peter Mandler gives the 2014 Emden Lecture at St Edmund Hall.

Episode Information

Series

People

Keywords

Department: St Edmund Hall

Date Added: 10/12/2014

Duration: 00:53:28

Download

Crohn's disease

Series

Autoimmune Disease

Embed

Professor Alison Simmons tells us about her research on Crohn's disease

Professor Alison Simmons is interested in the molecular aspects of innate immune recognition, the primitive arm of the immune system that defends the host from infection by other organisms in a non-specific manner. Defects in the innate immune system can result in difficulty clearing infections but also in inflammation.

Creative Commons Licence

Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series

People

Keywords

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 07:09:00

Download

Asthma

Series

Translational and Clinical

Embed

Airway inflammation

Ian Pavord is Professor of Respiratory Medicine and has been joint Chief Medical Advisor to Asthma UK since May 2008. He has developed new techniques to get a better idea about airway inflammation and uses this information to investigate the best treatments to prevent asthma attacks.

Creative Commons Licence

Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series

Translational and Clinical

People

Keywords

Department: Nuffield Department of Clinical Medicine

Date Added: 10/12/2014

Duration: 07:05:00

Download

Pneumococcal diseases

Series

Global Health

Embed

Genetics and genomics of Streptococcus pneumoniae

Angela Brueggemann's main focus is using high-throughput genotyping and whole genome sequencing techniques and unique collections of isolates to understand pneumococcal evolution, especially evolutionary changes related to antimicrobial and vaccine selective pressures.