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Statistical methods used to map malaria and other infectious diseases

Series
Malaria Atlas Project
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Ewan Cameron and Sam Bhatt from the Nuffield Department of Population Health discuss statistical methods used to map malaria and other infectious diseases.

Episode Information

Series
Malaria Atlas Project
People
Ewan Cameron
Sam Bhatt
Keywords
Health
Medicine
malaria
Department: Medical Sciences Division
Date Added: 28/04/2017
Duration: 00:48:48

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Malaria Atlas Project

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Malaria Atlas Project
Featuring researchers from the Malaria Atlas Project at the University of Oxford, this series of podcasts looks at some of the statistical methods that can be used to model malaria and other infectious diseases globally, as well as statistical modelling more generally.

The Malaria Atlas Project (MAP) brings together researchers based around the world with expertise in a wide range of disciplines from public health to mathematics, geography and epidemiology. Their task is to generate new and innovative methods of mapping malaria risk, ultimately to produce a comprehensive range of maps and estimates that will support effective planning of malaria control at national and international scales.

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Sir Roger Bannister, athlete and neurologist (Exeter College, 1946)

Series
Alumni Voices
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Sir Roger Bannister relives running the first sub-four-minute mile in a special podcast to mark the anniversary of his extraordinary achievement in May 1954.
Sir Roger Bannister relives running the first sub-four-minute mile in a special podcast to mark the anniversary of his extraordinary achievement in May 1954. He describes his training and how the record-breaking run (3 minutes 59.4 seconds) unfolded at the Iffley Road track in Oxford. Sir Roger mentions other highlights from his athletic career, and explains how he developed as a runner while studying at Oxford, where he read medicine at Exeter and Merton.

After retiring from running, Sir Roger focussed on his medical and academic career. He talks about his research interests and varied experiences, including his pioneering work on the autonomic nervous system, and focusing on heat illness when he was on army service in Aden. From 1985 to 1993, Sir Roger was Master of Pembroke in Oxford.

As well as inspiring generations of runners, Sir Roger has also had a wider impact upon sport. When he was chairman of the Sports Council in the 1970s he introduced the first anabolic steroid tests for athletes. In 2017, Sir Roger was made a Companion of Honour for his services to sport.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Alumni Voices
People
Roger Bannister
Keywords
running
sport
Medicine
neurology
Exeter
merton
Pembroke
Department: Alumni Office
Date Added: 28/04/2017
Duration: 00:16:07

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The enemy of my enemy is still my enemy: the polarized media landscape in Syria

Series
Reuters Institute for the Study of Journalism
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Rima Marrouch, freelance journalist for Reuters, BBC, CBS, and Al Jazeera, gives a talk for the Reuters Seminar Series, Introduction by Richard Sambrook. Please note, that there are videos within this presentation which may sound distorted.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Reuters Institute for the Study of Journalism
People
Rima Marrouch
Keywords
politics
reuters
journalism
syria
media
Department: Department of Politics and International Relations (DPIR)
Date Added: 28/04/2017
Duration: 00:21:46

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Dr Jeffrey Aronson

Series
Trust the Evidence
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Professor Carl Heneghan, Director of the Centre for Evidence-Based Medicine, in conversation with Dr. Jeffrey Aronson, President Emeritus and Honorary Fellow, British Pharmacological Society, and Consultant Physician.
Professor Carl Heneghan, Director of the Centre for Evidence-Based Medicine, in conversation with Dr. Jeffrey Aronson, President Emeritus and Honorary Fellow, British Pharmacological Society, and Consultant Physician, Nuffield Department of Primary Care Health Sciences, University of Oxford.

Trust the Evidence is a new podcast series presenting conversations with individuals interested in improving healthcare through the use of better evidence.

Send us your thoughts and feedback: cebm@phc.ox.ac.uk. You can also listen to previous episodes here.

Edited and produced by Alice Rollinson.

Episode Information

Series
Trust the Evidence
People
Carl Heneghan
Jeffrey Aronson
Keywords
Centre for Evidence-Based Medicine
Department: Centre for Evidence-Based Medicine
Date Added: 28/04/2017
Duration: 00:16:09

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Curiosity’s Search for Ancient Habitable Environments at Gale Crater, Mars

Series
Earth Sciences
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4th Annual Lobanov-Rostovsky Lecture in Planetary Geology delivered by Professor John Grotzinger, Caltech, USA
The Mars Science Laboratory rover, Curiosity, touched down on the surface of Mars on August 5, 2012. Curiosity was built to search and explore for habitable environments and has a lifetime of at least one Mars year (~23 months), and drive capability of at least 20 km. The MSL science payload can assess ancient habitability which requires the detection of former water, as well as a source of energy to fuel microbial metabolism, and key elements such carbon, sulfur, nitrogen, and phosphorous. The search for complex organic molecules is an additional goal and our general approach applies some of the practices that have functioned well in exploration for hydrocarbons on Earth. The selection of the Gale Crater exploration region was based on the recognition that it contained multiple and diverse objectives, ranked with different priorities, and thus increasing the chances of success that one of these might provide the correct combination of environmental factors to define a potentially habitable paleoenvironment. Another important factor in exploration risk reduction included mapping the landing ellipse ahead of landing so that no matter where the rover touched down, our first drive would take us in the direction of a science target deemed to have the greatest value as weighed against longer term objectives, and the risk of mobility failure. Within 8 months of landing we were able to confirm full mission success. This was based on the discovery of fine-grained sedimentary rocks, inferred to represent an ancient lake. These Fe-Mg-rich smectitic mudstones preserve evidence of an aqueous paleoenvironment that would have been suited to support a Martian biosphere founded on chemolithoautotrophy and characterized by neutral pH, low salinity, and variable redox states of both iron and sulfur species. The environment likely had a minimum duration of hundreds to tens of thousands of years. In the past year simple chlorobenzene and chloroalkane molecules were confirmed to exist within the mudstone. These results highlight the biological viability of fluvial-lacustrine environments in the ancient history of Mars and the value of robots in geologic exploration.

Episode Information

Series
Earth Sciences
People
John Grotzinger
Keywords
mars rover
curiosity mars rover
Mars Science Laboratory rover
mars
habitable environments
planets
ancient habitability
water
microbial metabolism
carbon
sulfur
nitrogen
and phosphorous
complex organic molecules
hydrocarbons
Gale Crater
environmental factors
paleoenvironment
Department: Department of Earth Sciences
Date Added: 27/04/2017
Duration: 01:09:28

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The Origins and Evolution of Exoplanet Atmospheres and Oceans

Series
Earth Sciences
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3rd Annual Lobanov-Rostovsky Lecture in Planetary Geology delivered by Professor Raymond T Pierrehumbert.
Atmospheres are dynamic entities, formed from the volatile substances that accrete when a planet is formed and later in its history, cooked out in the hot-high pressure interior of the planet, and exchanging with the interior through crustal processes (for planets which have a solid surface) or mixing into the deep interior (for fluid planets). Loss of atmosphere to space is also a major mechanism whereby the chemical composition of entire planets evolve. There is thus no distinct boundary between the disciplines of planetary geology and planetary atmospheres, and the dawning age of exoplanet discovery has made it even more essential to think across the boundaries of the two disciplines. The likely characteristics of known exoplanets greatly expand the range of substances that have to be thought of as atmospheric components, with many things thought of as “rocks and minerals” on Earth being atmospheric or cloud forming substances. There are planets hot enough to have permanent magma oceans which may give rise to rock vapor atmospheres, and others where clouds may be formed of enstatite or even sapphire (or more prosaically, corundum). Some of these atmospheres are supersonic and local; others may be global and subsonic. There is also a host of new problems to be thought about in connection with “gas midgets,” which are mostly fluid but small enough that they need not have a hydrogen dominated composition. In this lecture, I will provide a survey of the emerging field of integrated planetary science, and conclude with some thoughts on how to train the next generation of planetary scientists to deal with the leading-edge problems of the future.

Episode Information

Series
Earth Sciences
People
Raymond T Pierrehumbert
Keywords
exoplanet
Planetary Geology
planetary atmospheres
Department: Department of Earth Sciences
Date Added: 27/04/2017
Duration: 00:57:20

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Curiosity’s Search for Ancient Habitable Environments at Gale Crater, Mars

Series
Oxford Physics Public Lectures
Embed
4th Annual Lobanov-Rostovsky Lecture in Planetary Geology delivered by Professor John Grotzinger, Caltech, USA

The Mars Science Laboratory rover, Curiosity, touched down on the surface of Mars on August 5, 2012. Curiosity was built to search and explore for habitable environments and has a lifetime of at least one Mars year (~23 months), and drive capability of at least 20 km. The MSL science payload can assess ancient habitability which requires the detection of former water, as well as a source of energy to fuel microbial metabolism, and key elements such carbon, sulfur, nitrogen, and phosphorous. The search for complex organic molecules is an additional goal and our general approach applies some of the practices that have functioned well in exploration for hydrocarbons on Earth. The selection of the Gale Crater exploration region was based on the recognition that it contained multiple and diverse objectives, ranked with different priorities, and thus increasing the chances of success that one of these might provide the correct combination of environmental factors to define a potentially habitable paleoenvironment. Another important factor in exploration risk reduction included mapping the landing ellipse ahead of landing so that no matter where the rover touched down, our first drive would take us in the direction of a science target deemed to have the greatest value as weighed against longer term objectives, and the risk of mobility failure. Within 8 months of landing we were able to confirm full mission success. This was based on the discovery of fine-grained sedimentary rocks, inferred to represent an ancient lake. These Fe-Mg-rich smectitic mudstones preserve evidence of an aqueous paleoenvironment that would have been suited to support a Martian biosphere founded on chemolithoautotrophy and characterized by neutral pH, low salinity, and variable redox states of both iron and sulfur species. The environment likely had a minimum duration of hundreds to tens of thousands of years. In the past year simple chlorobenzene and chloroalkane molecules were confirmed to exist within the mudstone. These results highlight the biological viability of fluvial-lacustrine environments in the ancient history of Mars and the value of robots in geologic exploration.

Episode Information

Series
Oxford Physics Public Lectures
People
John Grotzinger
Keywords
mars rover
curiosity mars rover
Mars Science Laboratory rover
mars
habitable environments
planets
ancient habitability
water
microbial metabolism
carbon
sulfur
nitrogen
and phosphorous
complex organic molecules
hydrocarbons
Gale Crater
environmental factors
paleoenvironment
Department: Department of Physics
Date Added: 27/04/2017
Duration:

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Spatio-temporal Optical Vortices

Series
Oxford Physics Public Lectures
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Physics Colloquium 10th March 2017 delivered by Professor Howard Milchberg, University of Maryland, USA
When an optical pulse propagating through a nonlinear medium exceeds a certain threshold power, it can focus itself and collapse, in theory, to a singularity. In practice, several physical mechanisms mitigate or arrest the catastrophic collapse and the pulse continues propagation as a filamentary structure. This scenario has played out in many nonlinear optics systems over decades: among them are air filamentation, relativistic self-focusing in plasmas, laser-material processing, and nonlinear generation of broadband light. Recently, we showed that self-focusing collapse and collapse arrest is universally accompanied by the generation of robust topological structures: spatio-temporal optical vortices (STOVs). I’ll describe our experiments and simulations leading to this result.

Episode Information

Series
Oxford Physics Public Lectures
People
Howard Milchberg
Keywords
optical pulse propagating
nonlinear mediums
singularity
filamentary structure
spatio-temporal optical vortices
stovs
Department: Department of Physics
Date Added: 27/04/2017
Duration: 00:57:08

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Learning new physics from a medieval thinker: Big Bangs and Rainbows

Series
Oxford Physics Public Lectures
Embed
Physics Colloquium 24 February 2017 delivered by Professor Tom McLeish FRS, Department of Physics and Institute for Medieval and Renaissance Studies, Durham University, UK
For the English polymath, Robert Grosseteste, light was the fundamental first form that gave dimensionality and stability to the material world. In a dozen scientific treatises written in the early 13th Century, he postulated a physics of light, colour and the rainbow. In his De luce (on light) he extends it to the origin of the Universe in what has been referred to as the ‘Medieval Big Bang’. His arguments are so taut that they can be translated into mathematics - our resulting numerical simulations show that Grosseteste’s model does actually work. He also described the method for developing a universal principle from repeated observations under controlled conditions and argued that the explanation needing fewer suppositions and premises was the best. In his theory of colour, we have found through close examination of the manuscript evidence for his De colore (on colour) and his De iride (on the rainbow) and a mathematical analysis of their content, that he presents the first three-dimensional theory of perceptual colour space.

In this talk, I introduce Robert Grossteste (ca 1170 -1253), the scientist, teacher, theologian and bishop and describe how a unique collaborative research approach has revealed new insights into his thought, particularly on light. An interdisciplinary team of historians, scientists, linguists and philosophers has developed techniques of joint reading of the medieval texts that have shown them to be logically consistent and founded on mathematically based models. We reflect on how a study of this extraordinary medieval science can help throw fresh light on the history of scientific thought, and bridge the current perception gap between the study of science and humanities.

Episode Information

Series
Oxford Physics Public Lectures
People
Tom McLeish
Keywords
Robert Grosseteste
light
colour
rainbow
de luce
medieval big bang
mathematics
de coloure
Department: Department of Physics
Date Added: 27/04/2017
Duration: 00:54:26

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