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Drug Discovery

Series
Translational Medicine
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Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders.
Professor Chas Bountra is interested in identifying and validating target proteins for drug discovery. Various technologies and strategies have allowed him to progress promising clinical candidates into Phase I, II, III studies, and to market. Drug candidates are first selected by screening compounds capable of binding to a target protein. Those compounds are then tested in various assay systems, healthy volunteers and finally in patients. Academic research excels at defining good target proteins. Pharmaceutical companies then facilitate the transition from basic research to clinical trials, producing new therapies for patients.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Chas Bountra
Keywords
Medicine
drug discovery
target validation
structural biology
disease
Department: Nuffield Department of Clinical Medicine
Date Added: 20/12/2010
Duration: 00:05:25

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Drug Discovery

Series
Translational and Clinical
Embed
Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders.
Professor Chas Bountra is interested in identifying and validating target proteins for drug discovery. Various technologies and strategies have allowed him to progress promising clinical candidates into Phase I, II, III studies, and to market. Drug candidates are first selected by screening compounds capable of binding to a target protein. Those compounds are then tested in various assay systems, healthy volunteers and finally in patients. Academic research excels at defining good target proteins. Pharmaceutical companies then facilitate the transition from basic research to clinical trials, producing new therapies for patients.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Chas Bountra
Keywords
Medicine
drug discovery
target validation
structural biology
disease
Department: Nuffield Department of Clinical Medicine
Date Added: 20/12/2010
Duration: 00:05:25

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Leverhulme Lecture 2010: The Future of Securitisation

Series
Law Faculty Podcasts
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Third and Final lecture in the 2010 Leverhulme Lecture series held in the Law Faculty, St Cross college in November 2010.

Episode Information

Series
Law Faculty Podcasts
People
Steven Schwarcz
Keywords
st cross
law
leverhulme lecture series
leverhulme
Department: Faculty of Law
Date Added: 20/12/2010
Duration: 00:50:23

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Leverhulme Lecture 2010: Regulating Complexity in Financial Markets

Series
Law Faculty Podcasts
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Second leverhulme lecture in the 2010 series held in the Law Faculty, St Cross College in November.

Episode Information

Series
Law Faculty Podcasts
People
Steven Schwarcz
Keywords
st cross
law
leverhulme lecture series
leverhulme
Department: Faculty of Law
Date Added: 20/12/2010
Duration: 00:56:03

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Leverhulme Lecture 2010: The Global Financial Crisis and Systematic Risk

Series
Law Faculty Podcasts
Embed
First of the Leverhulme Lectures held in the Law Faculty of St Cross College November 2010.

Episode Information

Series
Law Faculty Podcasts
People
Steven Schwarcz
Keywords
st cross
law
leverhulme lecture series
leverhulme
Department: Faculty of Law
Date Added: 20/12/2010
Duration: 00:37:29

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Earth Sciences

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Earth Sciences
Podcasts from the department of Earth Sciences.

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2009 Lecture 5: Normative Structures

Series
John Locke Lectures in Philosophy
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Fifth and final lecture in the 2009 John Locke lectures entitled Being Realistic about Reasons.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
John Locke Lectures in Philosophy
People
Thomas M Scanlon
Keywords
oxford
philosophy
john locke lecture series
john locke
Department: Faculty of Philosophy
Date Added: 20/12/2010
Duration: 00:59:51

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2009 Lecture 4: Epistemological Problems

Series
John Locke Lectures in Philosophy
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Fourth lecture in the 2009 John Locke Lecture series entitled Being Realistic about Reasons.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
John Locke Lectures in Philosophy
People
Thomas M Scanlon
Keywords
oxford
philosophy
john locke lecture series
john locke
Department: Faculty of Philosophy
Date Added: 20/12/2010
Duration: 00:59:31

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2009 Lecture 3: Motivation and the Appeal of Expressivism

Series
John Locke Lectures in Philosophy
Embed
Third lecture in the 2009 John Locke lecture series entitled Being Realistic about Reasons.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
John Locke Lectures in Philosophy
People
Thomas M Scanlon
Keywords
oxford
philosophy
john locke lecture series
john locke
Department: Faculty of Philosophy
Date Added: 20/12/2010
Duration: 00:59:29

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2009 Lecture 2: Normativity and Metaphysics

Series
John Locke Lectures in Philosophy
Embed
Second lecture in the 2009 John Locke lectures entitled Being Realistic about Reasons.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
John Locke Lectures in Philosophy
People
Thomas M Scanlon
Keywords
oxford
philosophy
john locke lecture series
john locke
Department: Faculty of Philosophy
Date Added: 20/12/2010
Duration: 00:52:15

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