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"Origins" - Complete Episode

Series
Big Questions - with Oxford Sparks
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The subject of origins is explored - from human fertilisation to the Big Bang. Includes parts 1, 2 and 3.

Episode Information

Series
Big Questions - with Oxford Sparks
People
Jo Dunkley
Alex Halliday
Suzannah Williams
Dagan Wells
Chris Lintott
Keywords
gravity
stars
cosmology
BigBang
darkmatter
darkenergy
universe
light
space
astrophysics
time
Reproduction
ovary
gestation
egg
germ cell
sperm
gamete
genetics
embryo
ovulation
fertilisation
Department: Mathematical, Physical and Life Sciences (MPLS)
Date Added: 09/10/2014
Duration: 00:27:17

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"Matters of Scale" Part 3 - Nanomedicine

Series
Big Questions - with Oxford Sparks
Embed
Dr Sonia Trigueros explains how she is using nanotechnologies to create targeted drug delivery systems. Chemotherapy is a particularly harmful treatment, with patients losing their hair and suffering from infections due to damage to their immune systems.
By using the unique properties of cancer cells, they can be used to deliver targeted therapy at a much reduced dose.

Episode Information

Series
Big Questions - with Oxford Sparks
People
Sonia Trigueros
Chris Lintott
Keywords
education
research
scale
nano
Physics
biology
Medicine
cancer
chemotherapy
bacteria
virus
carbon
Department: Mathematical, Physical and Life Sciences (MPLS)
Date Added: 08/10/2014
Duration: 00:08:48

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"Matters of Scale" Part 2 - Biology and the Problem with Scale

Series
Big Questions - with Oxford Sparks
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Dr Sylvia MacLain talks about how water creates a problem when researching biology. Structures can be studied when they are in solid form, but approximately 60% of our bodies are made of water.
Proteins, essential for life, are especially problematic as their entire function is related to their structure, which is different in solution. This means that no-one has yet been able to work out how they fold into ordered structures.

Episode Information

Series
Big Questions - with Oxford Sparks
People
Sylvia MacLain
Chris Lintott
Keywords
education
research
scale
water
biology
biochemistry
cells
protein folding
Department: Mathematical, Physical and Life Sciences (MPLS)
Date Added: 08/10/2014
Duration: 00:11:03

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"Matters of Scale" Part 1 - Extremes of Scale

Series
Big Questions - with Oxford Sparks
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Professors Pedro Ferreira and Alan Barr explain what scale means to them, from particle physics to the visible universe. At the subatomic level, gravity has a surprisingly large effect and particles are so small that they have no size.
But at the level of the universe, the speed of light is the only sensible measurement.

Episode Information

Series
Big Questions - with Oxford Sparks
People
Alan Barr
Pedro Ferreira
Chris Lintott
Keywords
education
research
scale
astrophysics
cosmology
particle physics
universe
ATLAS
LHC
CERN
light year
gravity
light
quark
dark matter
Department: Mathematical, Physical and Life Sciences (MPLS)
Date Added: 08/10/2014
Duration: 00:08:19

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“Not for Glory, not for Gain!” The Czech Glass Spartakiad Figurine, 1955

Series
Design for War and Peace: 2014 Annual Design History Society Conference
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This paper looks at the glass figurines of Czech artist Miloslav Klinger, made to commemorate the 1955 Prague Spartakiad, as complex sites of memory, craft and political propaganda.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Design for War and Peace: 2014 Annual Design History Society Conference
People
Rebecca Bell
Keywords
glass
craft
Czech
memory
folk
Department: Oxford Lifelong Learning
Date Added: 07/10/2014
Duration: 00:23:51

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Why is Oxford Determined to Change the Way We Discover New Medicines?

Series
Alumni Weekend
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Chas Bountra, a popular speaker at the recent Meeting Minds: Alumni Weekend in Asia, will explain how Oxford is creating a new ecosystem for drug discovery.

Episode Information

Series
Alumni Weekend
People
Chas Bountra
Keywords
Medicine
drugs
research and development
treatment
disease
Department: Alumni Office
Date Added: 07/10/2014
Duration: 00:43:13

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Richard Nixon’s Reputation: 40 years after Watergate

Series
Alumni Weekend
Embed
Nigel Bowles explores Nixon’s politics that achieved a synthesis of strategy, imagination, ideologies, and calculation rare among Presidents.

Episode Information

Series
Alumni Weekend
People
Nigel Bowles
Keywords
politics
Nixon
Watergate
Department: Alumni Office
Date Added: 07/10/2014
Duration: 00:55:14

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"Origins" Part 3 - Origins of Human Life

Series
Big Questions - with Oxford Sparks
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Drs Suzannah Williams and Dagan Wells explore the secrets and processes behind human fertilisation. Sperm and eggs must face huge challenges before they even meet. After fertilisation, they go on to form a small ball of cells with huge potential.

Episode Information

Series
Big Questions - with Oxford Sparks
People
Suzannah Williams
Dagan Wells
Chris Lintott
Keywords
education
research
oocyte
cell
human genetics
DNA
Reproduction
ovary
gestation
germ cell
sperm
gamete
embryo
fertilisation
Department: Mathematical, Physical and Life Sciences (MPLS)
Date Added: 07/10/2014
Duration: 00:08:40

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Tuberculous Meningitis

Series
Translational Medicine
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Tuberculous Meningitis
Professor Guy Thwaites is trying to improve outcomes for patients with tuberculous meningitis, the most severe form of tuberculosis. 100, 000 people a year get tuberculous meningitis and without treatment 100% of people with the disease will die.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Guy Thwaites
Keywords
guy thwaites
tuberculous meningitis
Department: Nuffield Department of Clinical Medicine
Date Added: 07/10/2014
Duration: 07:49:00

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Crohn's disease

Series
Translational Medicine
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Innate immune system
Professor Alison Simmons is interested in the molecular aspects of innate immune recognition, the primitive arm of the immune system that defends the host from infection by other organisms in a non-specific manner. Defects in the innate immune system can result in difficulty clearing infections but also in inflammation.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Alison Simmons
Keywords
alison simmons
crohns's disease
innate immunity
Department: Nuffield Department of Clinical Medicine
Date Added: 07/10/2014
Duration: 07:09:00

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