Skip to main content
Home

Main navigation

  • Home
  • Series
  • People
  • Depts & Colleges
  • Open Education

Main navigation

  • Home
  • Series
  • People
  • Depts & Colleges
  • Open Education

Understanding the Monsoon

Series
Oxford Physics Public Lectures
Embed
The 2015 Halley Lecture delivered by Professor Peter J. Webster

Each year the monsoons bring rainfall to nearly half the population of the planet. Small variations in monsoon rainfall can lead to flood or drought, feast or famine. Therefore, explaining the physics driving the monsoon and turning this knowledge into predictions is one of the great problems in science. In 1686 Sir Edmund Halley, with trade and navigation on his mind, suggested that the monsoon was driven by the buoyancy induced by the differential heating between the Indian Ocean and the landmass of South Asia. With a few embellishments, such as noting the importance of the rotation of Earth, his theory has stood the test of time. However, during the last 20 years, advances in our understanding of global fluid dynamics, suggest that a land-sea heating contrast is not sufficient. In fact, at the same latitudes of maximum monsoon summer rainfall, in other parts of the world there are deserts. Here we will develop an alternative, albeit simple, general theory of the monsoons and discuss how this may be translated into useful predictions and a greater understanding of how the monsoons will fair in a changing climate.

Episode Information

Series
Oxford Physics Public Lectures
People
Peter J. Webster
Keywords
Physics
atmospheric physics
Halley
monsoon
global fluid dynamics
climate change
flood
drought
Department: Department of Physics
Date Added: 30/07/2015
Duration:

Subscribe

Download

A deep breath in

Series
Translational and Clinical
Embed
Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people.
Dr Mona Bafadhel studies the pathophysiology of COPD (chronic obstructive pulmonary disease). There are broadly two inflammatory phenotypes of COPD that are clinically indistinguishable but have different treatment responses. Dr Bafadhel is working on the development of novel therapeutic strategies for COPD, particularly to treat the regular periods of worsened symptoms that patients experience.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Mona Bafadhel
Keywords
asthma
copd
pathophysiology
treatment
therapeutic strategies
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:04:40

Subscribe

Download

Chemistry, epigenetics and drugs

Series
Translational and Clinical
Embed
Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug.
Professor Paul Brennan research focusses on epigenetics: the mechanisms that control gene expression. He studies how chemical probes interfere with epigenetic enyzmes that can be targeted to treat various diseases. Epigenetics combined with disease biology will ultimately accelerate drug discovery.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Paul Brennan
Keywords
gene expression
Epigenetics
proteins
drug discovery
enzymes
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:03:57

Subscribe

Download

The genetics of metabolic diseases

Series
Translational and Clinical
Embed
A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function.
Professor Wyatt Yue explores how genetic defects lead to disease at the molecular level, by determining 3D structures and biochemical properties of enzymes and protein complexes linked to congenital genetic errors. Professor Yue works closely with clinicians and paediatricians to decipher the underlying genetic, biochemical and cellular mechanisms of these diseases. His long-term aim is to help design novel therapeutic approaches for metabolic diseases.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational and Clinical
People
Wyatt Yue
Keywords
matabolic
genetics
enzymes
biochemical
cellular
mechanisms
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:04:51

Subscribe

Download

The economics of tropical diseases

Series
Global Health
Embed
Economics and health are interlinked in many ways, as seen in the vicious cycle between poverty and ill health.
Dr Yoel Lubell leads the economic team at the MORU Mathematical and Economic Modelling Group, based in Bangkok, Thailand. His research focuses on the evaluation of diagnostics, treatments and vaccines for infectious diseases, with the aim of providing guidance on malaria elimination and control of artemisinin resistance in the Mekong region.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Global Health
People
Yoel Lubell
Keywords
economics
poverty
ill health
infectious diseases
malaria
artemisinin
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:05:23

Subscribe

Download

Getting the dose right

Series
Malaria
Embed
Too high a dose can result in toxicity and side-effects, too low a dose can cause the illness to come back and at worse develop resistance.
Professor Joel Tarning is Head of Clinical Pharmacology in our MORU Unit in Bangkok, Thailand. He's working towards drug dose-optimisation using novel pharmacometric modelling approaches. He is particularly interested in antimalarial treatments for children and pregnant women.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Malaria
People
Joel Tarning
Keywords
pharmacology
malaria
toxicity
drug resistance
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:07:00

Subscribe

Download

A deep breath in

Series
Translational Medicine
Embed
Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people.
Dr Mona Bafadhel studies the pathophysiology of COPD (chronic obstructive pulmonary disease). There are broadly two inflammatory phenotypes of COPD that are clinically indistinguishable but have different treatment responses. Dr Bafadhel is working on the development of novel therapeutic strategies for COPD, particularly to treat the regular periods of worsened symptoms that patients experience.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Mona Bafadhel
Keywords
asthma
copd
pathophysiology
treatment
therapeutic strategies
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:04:40

Subscribe

Download

Chemistry, epigenetics and drugs

Series
Translational Medicine
Embed
Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug.
Professor Paul Brennan research focusses on epigenetics: the mechanisms that control gene expression. He studies how chemical probes interfere with epigenetic enyzmes that can be targeted to treat various diseases. Epigenetics combined with disease biology will ultimately accelerate drug discovery.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Paul Brennan
Keywords
gene expression
Epigenetics
proteins
drug discovery
enzymes
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:03:57

Subscribe

Download

The genetics of metabolic diseases

Series
Translational Medicine
Embed
A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function.
Professor Wyatt Yue explores how genetic defects lead to disease at the molecular level, by determining 3D structures and biochemical properties of enzymes and protein complexes linked to congenital genetic errors. Professor Yue works closely with clinicians and paediatricians to decipher the underlying genetic, biochemical and cellular mechanisms of these diseases. His long-term aim is to help design novel therapeutic approaches for metabolic diseases.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Wyatt Yue
Keywords
matabolic
genetics
enzymes
biochemical
cellular
mechanisms
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:04:51

Subscribe

Download

The economics of tropical diseases

Series
Translational Medicine
Embed
Economics and health are interlinked in many ways, as seen in the vicious cycle between poverty and ill health.
Dr Yoel Lubell leads the economic team at the MORU Mathematical and Economic Modelling Group, based in Bangkok, Thailand. His research focuses on the evaluation of diagnostics, treatments and vaccines for infectious diseases, with the aim of providing guidance on malaria elimination and control of artemisinin resistance in the Mekong region.
Creative Commons Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK (BY-NC-SA): England & Wales; https://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Translational Medicine
People
Yoel Lubell
Keywords
economics
poverty
ill health
infectious diseases
malaria
artemisinin
Department: Nuffield Department of Clinical Medicine
Date Added: 28/07/2015
Duration: 00:05:23

Subscribe

Download

Pagination

  • First page
  • Previous page
  • …
  • Page 2086
  • Page 2087
  • Page 2088
  • Page 2089
  • Page 2090
  • Page 2091
  • Page 2092
  • Page 2093
  • Page 2094
  • …
  • Next page
  • Last page

Footer

  • About
  • Accessibility
  • Contribute
  • Copyright
  • Contact
  • Privacy
  • Login
'Oxford Podcasts' X Account @oxfordpodcasts | Upcoming Talks in Oxford | © 2011-2026 The University of Oxford